{"id":16887,"date":"2025-09-23T12:40:37","date_gmt":"2025-09-23T12:40:37","guid":{"rendered":"https:\/\/www.simpleonlinepharmacy.co.uk\/health-advice\/?p=16887"},"modified":"2025-09-23T12:40:38","modified_gmt":"2025-09-23T12:40:38","slug":"side-effects-switching-mounjaro-wegovy","status":"publish","type":"post","link":"https:\/\/www.simpleonlinepharmacy.co.uk\/health-advice\/weight-loss\/wegovy\/side-effects-switching-mounjaro-wegovy\/","title":{"rendered":"Side Effects When Switching from Mounjaro to Wegovy"},"content":{"rendered":"\n

If you\u2019ve decided to switch from Mounjaro to Wegovy<\/a>, you might be worried about side effects. Will there be any new ones? And does switching cause additional discomfort?<\/p>\n\n\n\n

We know starting a new treatment can be daunting. To help you navigate this change, here\u2019s what you can expect \u2013 and how to deal with potential side effects that may arise.<\/p>\n\n\n\n

Is it Safe to Switch From Mounjaro to Wegovy?<\/h2>\n\n\n\n

Yes, it is safe to switch from Mounjaro to Wegovy<\/a>, as long as a doctor or clinician has confirmed the medication is suitable for you.<\/p>\n\n\n\n

A healthcare professional will review information, like your medical history and current weight, before prescribing the medication. If you\u2019re buying Wegovy from an online provider, you\u2019ll have to fill in an online assessment form. For your safety, it\u2019s important you fill in this form accurately.<\/p>\n\n\n\n

When switching, you should leave a week between your last dose of Mounjaro and your first dose of Wegovy. If you take your last dose of Mounjaro on a Monday, you should not take your first dose of Wegovy until the following Monday. If possible, take it at the same time of day as your last dose.<\/p>\n\n\n\n

Both Wegovy and Mounjaro<\/a> follow the same dosing schedule (one injection per week, with four doses per pen).<\/p>\n\n\n\n

Is Wegovy Stronger Than Mounjaro?<\/h2>\n\n\n\n

It can be difficult to compare the \u201cstrength\u201d of two different medications.<\/p>\n\n\n\n

Both are GLP-1 receptor agonist medications. However, the medications work in different ways and have different active ingredients. Wegovy contains semaglutide, while Mounjaro contains tirzepatide.<\/p>\n\n\n\n

Some patients may find Wegovy to be more effective than Mounjaro, while others will find the opposite. In some cases, patients have reported their side effects were worse when using Mounjaro.<\/p>\n\n\n\n

Clinical trials have shown that, over a period of 72 weeks, patients using the highest Mounjaro dose can expect to see an average weight loss of around 22.5%<\/a>, while patients using Wegovy over 68 weeks saw an average of around 17%<\/a>. Based on this, it may be safe to say Mounjaro is more effective for weight loss than Wegovy, but these are averages. Some patients will lose more on Wegovy, while some will find Mounjaro more effective.<\/p>\n\n\n\n

Common Side Effects of Wegovy vs Mounjaro<\/h2>\n\n\n\n

The overall side effects of Wegovy<\/a> are similar to the side effects of Mounjaro<\/a>.<\/p>\n\n\n\n

\u201cSide effects are often similar to those experienced on Mounjaro, with things like nausea or stomach upset,\u201d explains Abdal Alvi, Simple\u2019s Chief Clinical Officer.<\/strong> \u201cBut if you have tolerated Mounjaro well, you\u2019ll likely manage Wegovy well too.\u201d<\/p>\n\n\n\n

For Wegovy, the most common side effects include:<\/p>\n\n\n\n