{"id":16894,"date":"2025-09-23T15:29:32","date_gmt":"2025-09-23T15:29:32","guid":{"rendered":"https:\/\/www.simpleonlinepharmacy.co.uk\/health-advice\/?p=16894"},"modified":"2026-02-13T11:22:16","modified_gmt":"2026-02-13T11:22:16","slug":"wegovy-vs-mounjaro-doses-conversion","status":"publish","type":"post","link":"https:\/\/www.simpleonlinepharmacy.co.uk\/health-advice\/weight-loss\/wegovy-vs-mounjaro-doses-conversion\/","title":{"rendered":"Wegovy vs Mounjaro Doses: Conversion Guide"},"content":{"rendered":"\n

Over the course of their treatment on Wegovy or Mounjaro, some patients might want to switch medications. Some may find they are not responding well to their chosen medication. Side effects and effectiveness can also vary depending on your own body chemistry.<\/p>\n\n\n\n

Recently, Eli Lilly has increased the price of Mounjaro. This means that more patients are looking to switch from Mounjaro to Wegovy<\/a>.<\/p>\n\n\n\n

But what dose should you switch to?<\/p>\n\n\n\n

Here, we compare the dose schedules of the two medications. We also explain how to switch to a higher strength of your new medication.<\/p>\n\n\n\n

Mounjaro vs Wegovy Dose Schedules<\/h2>\n\n\n\n

When you start either Wegovy<\/a> or Mounjaro, you will start at the lowest \u201cstarter\u201d dose and increase your dose each month. This gives your body time to adjust to the medication, making potential side effects less severe. They are both weekly injections.<\/p>\n\n\n\n

Once you reach the best dose that balances weight loss and side effects, you will stay at that level to reach your weight goal. Once you have achieved your target weight, you can maintain using your injection for the long-term.<\/p>\n\n\n\n

Some patients choose to maintain at a lower dose, if they don’t want to lose weight but still want to feel supported. At the end of treatment you can lower your dose monthly. This can make it easier to come off the medication.<\/p>\n\n\n\n

Is 0.25 mg Wegovy the same as 2.5 mg Mounjaro?<\/h2>\n\n\n\n

No, these two doses are not the same. It may seem simple to compare the starting dose of both of these medications. However, they are not directly comparable.<\/p>\n\n\n\n

Why There Is No Equivalent Dose Conversion?<\/h2>\n\n\n\n

Wegovy and Mounjaro<\/a> use two different active ingredients. Semaglutide is the active ingredient in Wegovy, and tirzepatide is the active ingredient in Mounjaro.<\/p>\n\n\n\n

Both of these compounds are glucagon-like peptide-1 (GLP-1) receptor agonists. This means they bond with naturally-occurring chemical receptors in your body, activating them.<\/p>\n\n\n\n

These receptors are responsible for feeling full when you eat food, meaning that these medications make you feel fuller even when you eat less. They also slow digestion, which helps you get more nutrition out of the food you do eat. This helps you with losing weight.<\/p>\n\n\n\n

However, tirzepatide has an additional function. It also acts as an agonist for glucose-dependent insulinotropic polypeptide (GIP) receptors as well. So it provides two pathways towards appetite suppression.<\/p>\n\n\n\n

This makes it difficult to compare the action of these two medications. So, if you are wondering \u201cwhat is the equivalent dose of Mounjaro and Wegovy?\u201d, it is a complicated question to answer.<\/p>\n\n\n\n

Semaglutide is also active at lower concentrations. You may notice that the highest dose of Wegovy (2.4 mg) is less than the starting dose of Mounjaro (2.5 mg). This does not correlate to effectiveness. It simply means that the doses are balanced to be effective without causing severe side effects.<\/p>\n\n\n\n