E45 Itch Relief 50g
  • E45 Itch Relief 50g

E45 Itch Relief 50g

Save 2% Now £3.99 Was £4.07

Product features

  • Designed to soothe skin and treat itching
  • Contains lauromacrogols and urea
  • Perfume free and dermatologically tested
  • Available in 50g, 100g or 500g
  • 500g comes with a pump-top bottle


Buy E45 Itch Relief 50g Online

You can buy E45 Itch Relief Cream online from our UK registered online pharmacy. Please read the associated information about this medication to make sure it's safe for you. You can then place your order. 

After completing any associated assessment form, our pharmacists can then review your order. If approved, we can dispatch it to your chosen address, with options for next-day delivery. If for any reason your order is not approved, a full refund is issued.

About E45 Itch Relief Cream 

E45 Itch Cream is a non-greasy moisturising cream, designed to help treat the itch associated with eczema and dermatitis, while also providing protection and moisturising to treat dry skin conditions.

E45 Itch Relief Cream has two active ingredients; lauromacrogol treats and soothes itchy skin, while the urea (a natural component of your skin’s defences) helps to create a barrier layer, locking in moisture and protecting your skin from further irritation.

E45 Itch Relief moisturises skin, and leaves it feeling calm and comfortable. E45 Itch Relief is suitable for the treatment of eczema, psoriasis and scaling skin conditions.

The 50g and 100g variations come in an easy-use tube, while the 500g comes in a pump-top bottle, for ease of application.


Some patients may find that E45 Itch Relief Cream isn’t as effective at treating their symptoms. Here at Simple Online Pharmacy, we have a number of alternatives available, including;

As with any change in medication, speak to your doctor before switching to an alternative skin care treatment.

E45 Itch Relief Cream Reviews

After using any treatment, it's helpful to let others know about your experience. Reviews of an item help other users know that medicines received are genuine, how well the treatment worked or any issues to be aware of. We invite our users to leave a review of both their treatment and of the service provided. Click on the Reviews tab to see if there has been feedback on this item.


How does E45 Itch Relief work?

When your skin itches, your body sends messages from your skin to let you know there is some form of irritation. E45’s anti-itch ingredient, lauromacrogols, are a topical anaesthetic. This means they cancel out these itch messages by lightly numbing the skin, preventing any signals from being sent. This helps to calm the skin down, and provides a mild pain-killing effect as well.

E45 also contains urea. This compound is found naturally on your skin, and helps to create the barrier layer of oils that are normally present on your skin. In dry skin conditions, however, this layer is often disrupted, leading to skin drying out and losing protection. Urea and paraffin both help to reinstate this layer, keeping skin protected and locking moisture into your skin.

Can I use E45 Itch Relief Cream for thrush?

E45 Itch Relief is designed for use on your skin, meaning it could be used for itching on the external gential area. However, it is not suitable for internal use, meaning you would need to be very careful about how it was applied, and it could not be used for internal itching. You would be better served with a specific thrush treatment, such as Canesten Duo.

Side Effects

E45 Itch Relief Cream Side Effects

As with all medications, some users may experience side effects when using E45 Itch Relief Cream - however, most will not.

While E45 cream is mostly well tolerated, some patients have reported a burning sensation, redness, itching or pus. This product is more likely to cause irritation if applied to broken or inflamed skin. 

Urea may cause other topically applied medicines to see increased penetration through the skin barrier when used at the same time. 

If you suspect an allergic reaction or if anything unusual happens, stop using the product and speak to your doctor, dermatologist or pharmacist. 

Info Leaflet

Before taking any medication, it is important to read the Patient Information Leaflet. You can find information leaflets for your medicines by typing them into the search bar at medicines.org, or by contacting us.


How To Use E45 Itch Relief Cream 

If using the pump-top bottle, twist pump to the open position. Press down on the pump to dispense cream. Twist the pump back to the locked position. This will prevent the cream drying out, and spills.

Apply to the affected skin twice per day. Spread thinly over skin until translucent to create a barrier layer.

If your symptoms persist, stop using this product and speak to your doctor, pharmacist or dermatologist.


Warnings for use of E45 Itch Relief Cream 

Do not use this product if you are allergic to lauromacrogols, urea or any of the other listed ingredients.

Do not use on acutely red, infected, inflamed or oozing skin.

Store below 25oC. Store out of sight and reach of children.

Do not smoke or go near open flames after application, as some of the ingredients are flammable. Clothes, bedclothes and furnishings which have been exposed to this product should be treated as a fire risk. Washing may reduce the buildup, but might not completely clear it.


E45 Itch Relief Cream Ingredients

Active Ingredients - Lauromacrogols 3.0%w/w and Urea 5.0%w/w 

Other Ingredients - Dimeticone, Phenyl Dimethicone, Liquid Paraffin, Cetyl Palmitate, Stearic Palmitic Acid, Octyldodecanol, Glycerol, Polysorbate, Carbomer, Trometamol, Benzyl Alcohol, Purified Water

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