HC45 cream
  • HC45 cream

HC45 cream

From £3.38

Medication features

  • Treatment for Eczema, Dermatitis & Insect Bites
  • Provides relief for up to 12 hours
  • Clinically proven & dermatologically tested


Buy HC45 Hydrocortisone Acetate Cream Online

You can buy HC45 Cream online from our UK registered online pharmacy. Please read the associated information about this medication to make sure it's safe for you. You can then place your order. 

After completing any associated assessment form, our pharmacists can then review your order. If approved, we can then dispatch it to your chosen address, with options for next-day delivery. If for any reason your order is not approved, a full refund is issued.

About HC45 Cream

Hc45 Cream is a topical steroid cream, an effective treatment for itching irritation and inflammation. Hc45 is suitable for the treatment of dermatitis, mild to moderate eczema and insect bites.

Hydrocortisone is a corticosteroid, which works by blocking the production of certain hormones. This means that it can prevent your body from reacting to some allergens, while also reducing swelling and itching that comes with allergic reactions and insect bites.

How does HC45 Hydrocortisone Cream work?

Hydrocortisone is a corticosteroid that works by reducing the inappropriate immune response in conditions such as allergic dermatitis, eczema and other inflammatory skin conditions. This helps prevent the body from attacking areas of the skin exposed to triggers it believes are harmful but are usually harmless.

Exposure to a trigger causes the body to react by marking the area for an immune system attack. Inflammation, itching redness and swelling are all signs of your immune system targeting the area.

By reducing the immune system response in the area of the body where the cream is applied, HC45 cream provides relief from the symptoms of allergic skin reactions.

How To Use HC45 Cream

Wash your hands before applying HC45 Cream.

Apply a thin layer over the affected area once or twice a day. Wash your hands after application.

Use this medicine only on your skin to cover the affected area. Do not cover with a dressing.

Do not use this medication for more than 7 days without speaking to your doctor.

HC45 Cream Summary


Apply a thin layer over the affected area once or twice a day.

Type of medicine

Corticosteroid cream


Reduces irritation and inflammation from allergic and immune responses

Active Ingredient



From £3.38

Side Effects

Can include hair growth, skin atrophy, local irritation


Some patients may find that HC45 Cream isn’t as effective at treating their symptoms. There are  a number of alternatives available, including;

Practical Tips

Dealing with eczema and dermatitis can be difficult. Follow these simple tips to help keep your skin conditions under control;

  1. Avoid triggers that flare up your eczema (for example, certain foods or using certain products).
  2. Try to avoid scratching your skin - if you are experiencing an itch, try tapping the itchy area instead.
  3. Try to use a moisturiser on your skin daily, and remember to moisturise after a bath/shower.
  4. If you are handling irritants such as detergents or bleach use gloves. Try to get gloves for sensitive skin, as some gloves contain powders or ingredients that can make skin conditions worse.
  5. Try to avoid extreme temperatures and humidity.
  6. You should ensure that you stay hydrated - drink lots of water.
  7. Try to use non-abrasive clothing fabrics such as cotton.
  8. After having a shower or a bath, pat dry your skin and re-apply your moisturiser. 
  9. Do not use body scrubs that are rough on your skin - this can cause damage to the skin surface, leading to further irritation
  10. Try to avoid hot and long baths/showers - these can cause damage to the skin surface.
  11. Try to avoid alcohol-containing antibacterial gels.

HC45 Hydrocortisone Cream Side Effects

As with all medications, some users may experience side effects when using HC45 Cream - however, most will not.

This medication contains cetostearyl alcohol, which may cause contact dermatitis or other local skin reactions.

This product may cause blurred vision, or local skin reactions such as dermatitis, hypertrichosis (hair growth), skin atrophy and rosacea. 

If you experience any side effects, including ones not listed here, stop using this medication and seek medical advice from your doctor or pharmacist.

HC45 Hydrocortisone Cream Reviews

After using any treatment, it's helpful to let others know about your experience. Reviews of an item help other users know that the medicines received are genuine, how well the treatment worked or any issues to be aware of. We invite our users to leave a review of both their treatment and the service provided. Click on the Reviews tab to see if there has been feedback on this item.

Info Leaflet

Before taking any medication, it is important to read the Patient Information Leaflet.


Warnings for use of HC45 Cream

Do not use this medication if you are allergic to any of the ingredients.

Do not use the cream on the eyes, face, anal or genital areas.

Do not use the cream on broken or infected skin, e.g impetigo, cold sores, acne, athletes foot or infected bites and stings.

Consult your doctor before using this medication if you are pregnant, or breastfeeding. 

Not suitable for children under 10 without medical advice.



HC45 Cream Ingredients

Active Ingredients - Hydrocortisone Acetate 1% w/w 

Other Ingredients - white soft paraffin, liquid paraffin, phenoxyethanol, purified water, cetomacrogol emulsifying wax with cetostearyl alcohol.

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