Paludrine tablets
  • Paludrine tablets

Paludrine Tablets

From £14.95

Medication features

  • Contains Proguanil Hydrochloride
  • Helps prevent the risk of malaria
  • Pharmacy medication

Overview

Buy Paludrine Tablets Online

Paludrine 100mg tablets are used to prevent malaria infection. Paludrine contains a medicine called proguanil hydrochloride. This belongs to a group of medicines called ‘antimalarials’ which can be used in certain parts of the world to help prevent malaria. This is a serious disease spread by infected mosquitoes.

Paludrine will give some degree of protection (prophylaxis) against malaria in certain countries. Paludrine can also be prescribed by a doctor to help suppress some types of malaria. Medicines to help prevent malaria (malaria prophylaxis) are recommended for:

  • People travelling to countries where malaria occurs.
  • People living in malaria areas who are not immune to malaria.

These people have little or no immunity to malaria, so they are at risk of severe attacks. 

You must get medical advice on which anti-malarial medicines to take. You must ask your doctor or pharmacist if Paludrine is suitable for the part of the world that you are visiting. In some countries, you may have to take Paludrine with another medicine for maximum protection.

Avoiding mosquito bites

When you are taking this medicine to prevent malaria, you should also reduce the chances of
being bitten by mosquitoes.

  • Wear light-coloured, long-sleeved clothing and long trousers when you are outside after sunset.
  • Use insect repellent creams or sprays on parts of your body not covered by clothing.
  • Sleep in a properly screened room or under a mosquito net.
  • Spray to kill any mosquitoes that may have entered rooms in spite of screening.

Signs of malaria

No medicine can be guaranteed to protect against malaria in every case. If you have a high temperature (fever) during your visit to a malaria area, or up to a year after returning home, you should suspect malaria. Contact a  doctor straight away and let him or her know that you have visited a malaria area.

Side Effects

Side Effects of Paludrine Tablets

Like all medicines, Paludrine can cause side effects, although not everybody gets them.

Allergic reactions
If you have an allergic reaction, stop taking Paludrine and get medical help or contact your doctor straight away. The signs may include:

  • Difficulty in breathing.
  • Swelling of the face, lips, tongue or throat which may cause difficulty in swallowing.
  • An itchy rash (similar to nettle rash or hives).

Other possible side effects

  • Stomach and gut - Stomach upsets, diarrhoea, constipation. These usually improve as treatment continues.
  • Mouth - Mouth ulcers and Inflamed mouth.
  • Skin - Skin reactions, including itching, peeling and rash, sometimes with swelling of the affected area.
  • Hair - Hair loss (sometimes reversible).
  • Blood - If you have kidney problems, Paludrine may cause changes to your blood. A reduced number of blood cells. This can lead to easy or unexplained bruising, bleeding, serious infections, or feeling very tired, weak or breathless.
  • Liver - Liver problems which may cause yellowing of your skin or the whites of your eyes.
  • Other - High temperature (fever). Inflammation of blood vessels, which can cause tiredness, weakness, loss of appetite, rash, ulcers, blood shot eyes, pain in the joints, breathlessness and weight loss.

Info Leaflet

Before taking any medication, it is important to read the Patient Information Leaflet. You can find information leaflets for your medicines by typing them into the search bar at medicines.org, or by contacting us.

Directions

Directions of use for Paludrine Tablets

If this medicine is from your doctor or pharmacist, take it exactly as they have told you.

Otherwise, follow the instructions below. If you do not understand the instructions, or you are not sure, ask your doctor or pharmacist.

When to start taking your medicine

  • Start taking this medicine one week before you enter the malaria area. If this is not possible, start taking this medicine at least two days before you enter the malaria area.
  • You must continue to take it during your stay.
  • You must keep taking this medicine for 4 weeks after leaving the malaria area.

Adults and children over 14 years

  • Take two tablets daily.

Children

  • Under 1 year (including babies who are being breast-fed): Take a quarter of a Paludrine tablet daily.
  • Ages 1 to 4 years: Take half a Paludrine tablet daily.
  • Ages 5 to 8 years: Take one Paludrine tablet daily.
  • Ages 9 to 14 years: Take one and a half Paludrine tablets daily.

How to take your tablets

  • Take the tablet(s) at the same time each day.
  • Take the tablet(s) after food.
  • Swallow the tablet(s), or part tablets, whole with a drink of water.
  • For a young child, the tablet(s) may be given crushed in milk, honey or jam.

Warnings

Warnings for Paludrine Tablets

Do not take Paludrine if you are allergic (hypersensitive) to proguanil hydrochloride or any of the other ingredients
of this medicine.

Check with your doctor or pharmacist before taking your medicine if you have ever had problems with your kidneys. This is because your doctor may give you a lower dose of Paludrine.

If you live in a country where malaria occurs, you may already be slightly immune to the disease. You must ask a doctor or pharmacist for advice before you take anti-malarial medicines.

Tell your doctor or pharmacist if you are taking any of the following medicines:

  • Warfarin or other medicines used to prevent blood clots. Paludrine may increase the effect of these medicines.
  • Antacids (aluminium, calcium and magnesium salts that are used to treat heartburn or indigestion). Antacids may reduce the amount of Paludrine absorbed from your gut. This may mean that the full dose of Paludrine is not absorbed into your body and it will not work properly. Therefore, you should take your antacid dose at least two hours before or after taking your Paludrine dose.
  • Boosted protease-inhibitors (medicines used in the treatment of viral infections, such as HIV/AIDS), as these may alter the levels of Paludrine in your body.

Ingredients

Ingredients in Paludrine Tablets

  • The active substance in Paludrine Tablets is proguanil hydrochloride. Each tablet contains 100 mg of proguanil hydrochloride.
  • The other ingredients are calcium carbonate, gelatin, magnesium stearate (E572) and maize starch.

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