Semaglutide (Wegovy)
  • Semaglutide (Wegovy)

Semaglutide

Medication features

  • Active ingredient in Weogvy and Ozempic
  • Reduces hunger and slows digestion
  • Used for weight loss and to manage type 2 diabetes

Overview

Buy Semaglutide for Weight Loss

You can buy Semaglutide injections online from our UK registered online pharmacy. Please read the associated information about this medication to make sure it's safe for you. You can then place your order.

After completing any associated assessment form, our pharmacists will review your order. If approved, we can dispatch it to your chosen address, with options for next-day delivery. If, for any reason, your order is not approved, a full refund will be issued.

About Semaglutide

Semaglutide’s UK launch in 2023 led to both Wegovy and Ozempic becoming available. Ozempic is a medicine licensed for treating type 2 diabetes, while Wegovy is licensed for weight loss. Novo Nordisk produces both and they both contain the active ingredient, Semaglutide. Ozempic can be prescribed for weight loss in some cases, but this would be off-licence.

These medicines come from a family of drugs known as GLP-1 agonists. They act on this receptor which causes the body to secrete more insulin, release less glucagon, and slow the transit of food through your digestive system. The result is reduced appetite and the feeling of being full for longer. In people with type 2 diabetes, this allows them to have more control over their blood sugar levels, while those using semaglutide for weight loss may find it easier to eat less.

Semaglutide is used to help people with a body mass index (BMI) greater than 35kg/m2 to lose weight. It is also used in those with a BMI greater than 30kg/m2 who also have weight-related health problems such as high blood pressure, high cholesterol, sleep apnoea, and reflux.

Currently, it is recommended to use these medications for a maximum of 2 years, and should be used alongside other weight loss measures like a healthy balanced diet and regular physical exercise. You should aim for 150 minutes of moderate exercise each week, involving a combination of aerobic exercise and strength training.

Wegovy is the first weight loss drug to be licensed for use to prevent cardiovascular events such as heart attacks and strokes. It is licensed for use in people with established cardiovascular disease and a BMI over 27kg/m2.

Semaglutide Doses

Wegovy is a form of semaglutide licensed for weight loss. It is given as a weekly injection using a prefilled injection pen. Doses start at 0.25mg once a week for 4 weeks, followed by 0.5mg once per week for 4 weeks.

This will increase to 1mg each week for 4 weeks. You will then move on to a dose of 1.7mg per week.

It is important to liaise with a healthcare professional as you may stay on this as a maintenance dose or you may increase further to a regular dose of 2.4mg per week.

Semaglutide Effectiveness

Semaglutide has been approved for use in the UK by the National Institute of Health and Care Excellence (NICE). Evidence from clinical trials indicates that you could reduce your weight by up to 10% when used alongside a healthy diet and regular exercise.

In a large clinical trial spanning several countries, Wegovy reduced the risk of serious adverse cardiovascular events by 20% compared to placebo.

In a trial involving 2,000 individuals dealing with obesity, two groups were compared. The first group used a combination of semaglutide, along with a diet and exercise plan, while the second group only made lifestyle changes without medication. After 68 weeks, it was observed that half of the participants using semaglutide lost 15% of their body weight, with nearly a third losing 20%. Participants who solely relied on lifestyle changes experienced an average weight loss of about 2.4%.

Semaglutide Side Effects

As with all medications, some patients may experience side effects when using semaglutide, though not everyone will. Some of these effects may go away as your body becomes accustomed to semaglutide.

Common side effects include:

  • Decrease in appetite
  • Burping
  • Gallstones
  • Constipation
  • Diarrhoea
  • Stomach upset
  • Hypoglycaemia (low blood sugar)
  • Nausea
  • Vomiting
  • Injection site reactions

Less Common Side Effects:

Rare Side Effects:

  • Angioedema

This is swelling of the lips and airways from an allergic reaction. If you feel that your breathing is restricted seek medical help immediately.

It is important to discuss any side effects with your doctor. It may be that alterations can be made to reduce the side effects that you experience.

There may be some concern that semaglutide increases the risk of cancer, in particular medullary thyroid carcinoma (MTC) and multiple endocrine neoplasia syndrome type 2 (MEN). A large cohort study in Scandinavia, Semglutide was found to have no increased risk of thyroid cancer. A further French review of multiple studies concluded that Semaglutide did not increase the risk of any cancer developing.

However, If you are still concerned or have a history of these conditions, you should speak to your doctor before using semaglutide.

Practical Tips for Using Semaglutide

Semaglutide works more effectively when combined with a healthy diet and increased physical activity.

  • A balanced diet should include 5 portions of fruit and vegetables each day.
  • Drink 6-8 glasses of water per day.
  • Base your meals around starchy carbs such as potatoes, bread, rice, or pasta.
  • Choose wholegrains, they are high in fibre and help you feel fuller for longer.
  • Aim for at least 2 portions of fish each week.
  • Opt for lean cuts of meat, or pulses.
  • Include some dairy or dairy alternatives.
  • Use unsaturated oils and spreads.
  • Cut down on sugar and salt.

Regular exercise has many benefits for your health. It can reduce your risk of health problems like heart disease, stroke, type 2 diabetes, and cancer. You should try to be active every day and get 150 minutes of moderate exercise each week. Moderate exercise is when your heart rate increases, you breathe faster, and feel warmer.

When you are getting started, increased physical activity doesn’t need to mean a trip to the gym - a half hour walk each day can help semaglutide to work, and make you more likely to be able to add more strenuous activity as you progress.

Try to vary your injection sites to prevent skin irritation and to make sure that the medicine is absorbed consistently.

Wegovy is a prescription medication and should be treated as such. It is always best to discuss any medications with your doctor. If you plan to buy Wegovy online, check that the site is secure and that your payments are safe. You will need a prescription from a licensed professional; a doctor, a nurse prescriber, a pharmacist, or another healthcare professional with a current licence to prescribe in the UK.

Use a reputable online pharmacy and answer all of their questions truthfully. Check that the pharmacy and pharmacist are registered with the General Pharmaceutical Council (GPhC); doctors are registered with the General Medical Council (GMC), and nurses with the Nursing and Midwifery Council (NMC).

Semaglutide Alternatives

If you are experiencing side effects or find that Wegovy does not suit you for any reason, there are alternative medications available. Speak with your doctor as you may need a different dose or a different medicine.

Mounjaro is an alternative medicine that can be bought online. It is from the same family of drugs as Wegovy and works in a similar way - though rather than semaglutide, the active ingredient is tirzepatide. You can read our comparison of the two medications here.

Everyone is different and responds to medicines differently. You may experience side effects with one medicine in the GLP-1 family but not with another.

Compare

Treatment Comparison

SaxendaXenicalOrlistatMysimba
IngredientLiraglutideOrlistat 120mgOrlistat 120mgNaltrexone/Bupropion
MechanismRegulates appetiteReduces fat absorptionReduces fat absorptionRegulates appetite
DoseInjected once dailyOne three times daily with mealsOne three times daily with mealsGradually increased to 4 tablets daily

Clinical Author and Reviewer

Author

Laura

Queen's University Belfast Bachelor of Medicine, Bachelor of Surgery (MBBS) | 2005-2010

Laura studied medicine at Queen's University Belfast and graduated in 2010. She has worked as a doctor since then, mainly in mental health. She is passionate about making medical information accessible to the general public.

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Mysimba

Medication Simple Online Pharmacy
8mg/90mg xMysimba x 112 Tablets £117.99

Wegovy

Medication Simple Online Pharmacy
Wegovy Pen x0.25mg - 1 Month £139.00
Wegovy Pen x0.25mg + 0.5mg - 2 Months £275.00
Wegovy Pen x1mg - 1 Month £149.00
Wegovy Pen x1.7mg - 1 Month £219.99
Wegovy Pen x2.4mg - 1 Month £253.99
Wegovy Pen x0.5mg - 1 Month £139.00
Wegovy Pen x1mg + 1.7mg - 2 Months £365.99
Wegovy Pen x1mg x 2 - 2 Months £298.00
Wegovy Pen x1mg x 3 - 3 months £447.00
Wegovy Pen x0.5mg + 1mg - 2 Months £285.00
Wegovy Pen x0.25mg + 0.5mg + 1mg - 3 Months £410.00
Wegovy Pen x2.4mg x 2 - 2 Months £507.98
Wegovy Pen x0.25mg x2 - 2 Month £275.00
Wegovy Pen x0.25mg x3 - 3 Month £410.00
Wegovy Pen x0.5mg x2 - 2 Month £275.00
Wegovy Pen x0.5mg x3 - 3 Month £410.00
Wegovy Pen x1.7mg x2 - 2 Month £439.98
Wegovy Pen x1.7mg x3 - 3 Month £659.97
Wegovy Pen x2.4mg x3 - 3 Month £761.97
Wegovy Pen x1.7mg + 2.4mg - 2 Months £473.98
Wegovy Pen x1mg + 1.7mg - 2 Months £385.00

Ozempic

Medication Simple Online Pharmacy
Wegovy (Ozempic Equivalent) x0.25mg -1 Month Wegovy £149.00
Wegovy (Ozempic Equivalent) x0.5mg - 1 Month Wegovy £149.00
Wegovy (Ozempic Equivalent) x1mg - 1 Month Wegovy £169.00
Wegovy (Ozempic Equivalent) x1.7mg - 1 Month Wegovy £224.00
Wegovy (Ozempic Equivalent) x2.4mg - 1 Month Wegovy £269.00
Mounjaro (aka Zepbound) x2.5mg - 1 Month Starter £149.00
Mounjaro (aka Zepbound) x5mg - 1 Month Starter £149.00
Wegovy (Ozempic Equivalent) x0.25mg x2 - 2 Month Wegovy £298.00
Wegovy (Ozempic Equivalent) x0.25mg x3 - 3 Month Wegovy £447.00
Wegovy (Ozempic Equivalent) x0.5mg x2 - 2 Month Wegovy £298.00
Wegovy (Ozempic Equivalent) x0.5mg x3 - 3 Month Wegovy £447.00
Wegovy (Ozempic Equivalent) x1.7mg x2 - 2 Month Wegovy £439.98
Wegovy (Ozempic Equivalent) x1.7mg x3 - 3 Month Wegovy £659.97
Wegovy (Ozempic Equivalent) x1mg + 2.4mg - 2 Months Wegovy £473.98
Wegovy (Ozempic Equivalent) x1mg + 1.7mg - 2 Months Wegovy £385.00

Mounjaro

Medication Simple Online Pharmacy
Starter xMounjaro 2.5mg GREY Pen X 1 £139.00
5mg xMounjaro 5mg PURPLE Pen X 1 £139.00
Starter xMounjaro 2.5mg GREY Pen X 1 + Mounjaro 5mg PURPLE Pen X 1 £275.00
7.5mg xMounjaro 7.5mg GREEN Pen X 1 £169.99
10mg xMounjaro 10mg PINK Pen X 1 £189.99
12.5mg xMounjaro 12.5mg BLUE Pen X 1 £245.00
15mg xMounjaro 15mg ORANGE Pen X 1 £245.00
10mg xMounjaro 10mg PINK Pen X 2 £377.99
10mg xMounjaro 10mg PINK Pen X 3 £569.97
15mg xMounjaro 15mg ORANGE Pen X 3 £720.00
5mg xMounjaro 5mg PURPLE Pen X 2 £275.00
5mg xMounjaro 5mg PURPLE Pen X 3 £410.00
7.5mg + 10mg xMounjaro 7.5mg GREEN Pen X 1 + Mounjaro 10mg PINK Pen X 1 £359.98
12.5mg + 15mg xMounjaro 12.5mg BLUE Pen x 1 + Mounjaro 15mg ORANGE Pen X 1 £475.00
7.5mg xMounjaro 7.5mg GREEN Pen X 2 £318.00
7.5mg xMounjaro 7.5mg GREEN Pen X 3 £477.00
12.5mg xMounjaro 12.5mg BLUE Pen X 2 £490.00
12.5mg xMounjaro 12.5mg BLUE Pen X 3 £735.00
15mg xMounjaro 15mg ORANGE Pen X 2 £490.00
2.5mg xMounjaro 2.5mg GREY Pen X 2 £275.00
2.5mg xMounjaro 2.5mg GREY Pen X 3 £415.00
5mg + 7.5mg xMounjaro 5mg PURPLE Pen X 1 + Mounjaro 7.5mg GREEN Pen X 1 £308.99
10mg + 12.5mg xMounjaro 10mg PINK Pen X 1 + Mounjaro 12.5mg BLUE Pen X 2 £434.99

Tirzepatide

Medication Simple Online Pharmacy
2.5mg x1 Month Mounjaro £159.00

Zepbound

Medication Simple Online Pharmacy
Starter x1 Month Mounjaro £159.00
Starter x2 Month Mounjaro (2.5+5mg) £310.00

Saxenda

Medication Simple Online Pharmacy Pharmacy2U
Treated
Saxenda Pen Only (No Needles) x 1 £54.00
£75.00 £75.00
Saxenda Pen Only (No Needles) x 2 £106.00
N/A £140.00
Saxenda Pen Only (No Needles) x 5 x3 £207.00
N/A £200.00
Saxenda Pen Only (No Needles) x 4 £212.00
N/A £250.00
Saxenda Pen Only (No Needles) x 5 x5 £375.00
£319.99 £300.00
Pen + Sharps Bin (no needles) x 1 - + 1 x Sharps Bin (no needles) £57.00
Pen + Sharps Bin (no needles) x 2 - + 1 x Sharps Bin (no needles) £109.00
Pen + Sharps Bin (no needles) x 3 - + 1 x Sharps Bin (no needles) £162.00
Pen + Sharps Bin (no needles) x 4 - + 1 x Sharps Bin (no needles) £215.00
Pen + Sharps Bin (no needles) x 5 - + 1 x Sharps Bin (no needles) £257.00
Pen + Sharps Bin + Replacement Needle Heads x 1 - + 1 x Sharps Bin + 100 Needles £60.00
Pen + Sharps Bin + Replacement Needle Heads x 2 - + 1 x Sharps Bin + 100 Needles £112.00
Pen + Sharps Bin + Replacement Needle Heads x 3 - + 1 x Sharps Bin + 100 Needles £164.00
Pen + Sharps Bin + Replacement Needle Heads x 4 - + 1 x Sharps Bin + 100 Needles £217.00
Pen + Sharps Bin + Replacement Needle Heads x 5 - + 1 x Sharps Bin + 100 Needles £259.00
Pen + Replacement Needle Heads x 1 - + 1 x Needles £58.00
Pen + Replacement Needle Heads x 2 - + 100 Needles £110.00
Pen + Replacement Needle Heads x 3 - + 100 Needles £163.00
Pen + Replacement Needle Heads x 4 - + 100 Needles £216.00
Pen + Replacement Needle Heads x 5 - + 100 Needles £258.00
Saxenda Pen Only (No Needles) x 10 £503.00
Pen + Sharps Bin (no needles) x 10 - + 1 x Sharps Bin (no needles) £506.00
Pen + Sharps Bin + Replacement Needle Heads x 10 - + 1 x Sharps Bin + 100 Needles £508.00
Pen + Replacement Needle Heads x 10 - +100 Needles £519.00

Semaglutide

Medication Simple Online Pharmacy
Wegovy x0.25mg -1 Month Wegovy £149.00
Wegovy x0.25mg x2 - 2 Month Wegovy £298.00
Wegovy x0.25mg x3 - 3 Month Wegovy £447.00
Wegovy x0.5mg - 1 Month Wegovy £149.00
Wegovy x0.5mg x2 - 2 Month Wegovy £298.00
Wegovy x0.5mg x3 - 3 Month Wegovy £447.00
Wegovy x1mg - 1 Month Wegovy £169.00
Wegovy x1mg + 2.4mg - 2 Months Wegovy £473.98
Wegovy x1mg + 1.7mg - 2 Months Wegovy £385.00
Wegovy x1.7mg - 1 Month Wegovy £224.00
Wegovy x1.7mg x2 - 2 Month Wegovy £439.98
Wegovy x1.7mg x3 - 3 Month Wegovy £659.97
Wegovy x2.4mg - 1 Month Wegovy £269.00
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