• Orlos
  • Orlos


From £14.85

Medication features

  • Weight loss aid
  • Reduces the absorption of fat from food
  • Each capsule contains 60mg orlistat
  • Clinically Proven
  • For use by adults with a BMI of 28 and above

We have moved Orlos to our Orlistat page. To order Orlos, please click here to go to our Orlistat page and pick the 60mg strength during checkout.


Buy Orlos Weight Loss Tablets Online

You can request to buy Orlos tablets online from our UK registered online pharmacy. This is classed as a ‘Pharmacy’ medicine, which means you have to complete a short online questionnaire for our pharmacists to review. If your order is approved, our pharmacy team will dispatch the medicine to your delivery address using discreet packaging. 

What is Orlos?

Orlos is a medicine that can be taken regularly to help you lose weight alongside a reduced-calorie, lower-fat diet. It contains the active ingredient orlistat. This is suitable for people over 18 years old who are overweight and have a BMI of 28 or above.

For every 2kg you lose from dieting alone, Orlos can help you lose up to 1kg more. 

How to take Orlos

Before starting this medicine, you should decide ahead of time which day to start the capsules. This gives you a chance to start to reduce your calories and fat intake before taking the capsules. Doing so allows your body to have a few days to adjust to the new calorie-controlled diet.

The usual dose of Orlos is to take one capsule three times a day with meals. You can take it before, during, or up to one hour after each meal. There is no need to take a dose if you miss a meal or eat a meal containing no fat. 

Orlos should not be taken for more than 6 months. If you do not lose weight after taking the tablets for 12 weeks, contact your doctor or pharmacist for advice.

How does it work?

The active ingredient is designed to specifically target fat in your digestive system. It blocks enzymes in your digestive system from breaking down and absorbing the fat that you eat. This means that instead of being absorbed into the body, the fat passes through your digestive system and passes out with your stools. Research suggests around a third to a quarter of the fat you eat with Orlos will not be absorbed by the body. 

Studies estimate that orlistat stops around a third of the fat you eat from being absorbed by the body. Combined with healthy eating and an exercise program, this can be an effective weight loss plan. Orlos can reduce the absorption of certain vitamins, so you should take a multivitamin when using this medicine.


Orlos vs Alli: is Orlos the same as Alli?

Orlos and Alli are both branded weight loss pills. Both brands contain the same active ingredient and strength - orlistat 60mg. They are both brands of the same medicine produced by different manufacturers. The only significant difference is that Orlos is far cheaper than Alli.  You can request to order the prescription-only 120mg versions Xenical or orlistat from our online doctor weight loss clinic.

Is Orlos effective for weight loss?

The active ingredient in Orlos has been shown to be an effective aid for weight loss. Studies show that overweight people lose significantly more weight when taking orlistat alongside diet and exercise compared to taking placebo alongside diet and exercise. There is also evidence that for every 2kg you lose from dieting alone, taking Orlos can help you lose up to 1kg more.

How do you take Orlos?

One capsule should be taken three times a day with main meals. It can be taken before, during or within an hour of finishing a meal. There is no need to take a dose if you skip a meal or eat a meal containing no fat. You should contact your doctor or pharmacist for advice if you do not lose weight after taking the tablets for 12 weeks.

Does Orlistat make you lose weight?

Orlistat can be used as an effective weight loss aid. However, it should always be used alongside a low-fat, reduced-calorie diet and exercise.

Can I buy Orlos over the counter?

Orlos is available to buy over the counter or you can buy Orlos online at our UK registered online pharmacy. Simply fill an online questionnaire for our pharmacists to review. If approved, your medicine will be dispatched discreetly to your chosen address. You can also order the generic version of the medicine, orlistat, online from our online doctors.

Side Effects

Orlos Side Effects

Orlos works by reducing the amount of fat your body absorbs from food. This fat passes out of your body with your stools and can cause problems with bowel movements. Common side effects include oily stools, sudden bowel motions, soft stools, and wind. 

Eating high-fat meals can increase the risk of experiencing these side effects. You can try to minimise these side effects by reducing the fat content of your meals.

Read the patient information leaflet to see further information on the possible side effects associated with Orlos capsules. If you notice any unusual or severe side effects, contact your doctor or pharmacist for medical advice.




You should not take this medicine if you are pregnant or breastfeeding. People with food absorption problems, or a condition called cholestasis, should not take this medicine. If you have kidney disease or diabetes, you should contact your doctor before taking Orlos. 

Certain medicines can interact with Orlos. You should not take Orlos if you’re taking a medicine called ciclosporin, a medicine called acarbose, or any blood thinners (such as warfarin). See the patient information leaflet for further advice on Orlos and other conditions and medicines.

The oral contraceptive pill may be less effective if you experience severe diarrhoea while taking Orlos. You should use an extra method of contraception if you experience severe diarrhoea as a side effect.

Orlos should only be taken by people with a BMI over 28.

Order within for guaranteed next day delivery options

ClosePrice Checker
From £14.85
The variation selected is currently out of stock.
Item added to bag. Click here to view bag.
Please select a size from above to proceed.
There are NHS prescriptions in your basket. Please complete the order first or remove NHS prescriptions from the basket.
Copyright © 2013 - 2024 Simple Online Pharmacy Ltd. All rights reserved.
Data security and protection policies available by request.
  • Digital Clinical
  • LegitScript approved
  • Registed Pharmacy
  • NHS pharmacy
  • Visa
  • mastercard