Mounjaro vs Wegovy

What is Mounjaro?

Mounjaro, a medication available only on prescription, has been developed to help adults in managing their weight and address issues of obesity. The main ingredient in Mounjaro is Tirzepatide, which acts as a glucagon-like peptide-1 (GLP-1) receptor agonist. This substance works by mimicking a natural hormone in our bodies that is responsible for regulating our appetite and food intake, resulting in a reduction in calorie consumption and subsequent weight loss. It is important to note that Mounjaro is not a standalone solution, but should be used in conjunction with a lower-calorie diet and increased physical activity for optimal results.

Understanding Wegovy

Similar to Mounjaro, Wegovy also harnesses the potency of GLP1s, with Semaglutide as its active ingredient. It has received approval in the US, EU and the UK, becoming the newest drug in the sphere of chronic weight management solutions for adults.

Complementing a balanced diet and regular exercise, Wegovy operates by managing the individual’s appetite and food intake. This function mirrors that of Mounjaro, underpinning the similar roles both medications play in weight management. It’s critical to note that whilst both drugs share similarities in composition and function, their impacts may differ from person to person, and should not replace lifestyle changes but support them.

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Comparing Efficacy

As we take a look at the effectiveness of Mounjaro and Wegovy, it’s important to remember that despite being the same class of drug, and serving the same function, the impact can differ from person to person. Research has indicated that these medications can contribute to significant weight loss over a period. The effectiveness was gauged by noting the percentage of participants who achieved a minimum of 5% weight reduction.

While Wegovy has been shown to achieve around ~15% body weight loss on average for patients, Mounjaro has shown to help its users achieve ~20% body weight loss.

However, it’s pivotal to bear in mind that the results are greatly dependent on lifestyle modifications, with diet and exercise playing a crucial role. Therefore, the maximum benefit from these medications can be achieved when they are used as part of a holistic approach to weight management that includes a healthy diet and regular physical activity. In essence, while both Mounjaro and Wegovy exhibit promising results, individual responses may vary, underlining the importance of personalised medical advice.

Dosage Differences

Whilst both Mounjaro and Wegovy contain Semaglutide as their active ingredient, they differ in their dosage recommendations. The commencement dose for Mounjaro is suggested at 2.5 mg administered once per week, whereas Wegovy is advised to start at a dose of 0.25 mg weekly.

Over time, the dosage of both these medications is progressively increased based on individual response and tolerance. It is of utmost importance to adhere strictly to the dosage plan outlined by your healthcare professional and avoid any self-adjustments without prior medical guidance.

This titrated dose helps avoid side effects while using the treatment.

The titration of Wegovy is from 0.25mg > 0.5mg > 1mg > 1.7mg > 2.4mg.

The tiration of Mounjaro is from 2.5mg > 5mg > 7.5mg > 10mg > 12.5mg > 15mg.

Mounjaro vs Wegovy dosage

Side Effects

Just like any other medication, Mounjaro and Wegovy, whilst generally well-tolerated, do come with their own set of potential side effects. These could range from minor issues such as nausea, vomiting, diarrhoea, constipation, and discomfort in the abdominal region. Though these are common, they should not be disregarded and it’s advisable to keep your healthcare provider informed about any discomfort you may experience.

On rare occasions, patients could encounter more severe side effects. These could include pancreatitis, gallbladder disease, and even kidney injury. Whilst these side effects are not commonplace, their potential occurrence reinforces the need for close monitoring and regular check-ups with your healthcare provider throughout your weight loss journey.

For more information on each of the drugs side effects, and how to manage them, you can read about Wegovy side effects, and Mounjaro side effects in our deep dives into these areas.

Accessibility and Cost

Both treatments can be accessed via our UK registered online doctor service.

While there have been some supply issues to heavy demand, these are expected to ease. Prices can range from around £160/month to £295/month depending on drug and strength.

Highest efficacy is typically experienced at the higher doses.

Final Considerations

In evaluating Mounjaro and Wegovy, it’s imperative to consider multiple facets such as efficacy, dosage, potential side effects, cost, and availability. Nevertheless, the eventual decision should be based on a medical assessment.

Both these medications offer promising potential as weight management tools, but it’s crucial to remember that they are not substitutes for balanced nutrition and regular physical activity, but rather, components of a broader weight management plan.

It’s vital to maintain a holistic view of your weight loss journey, and keep in mind that successful weight management is a combination of medication, healthy diet, and exercise. Our Renu app can help with that!

Remember, informed decision-making coupled with professional medical advice is the cornerstone of a successful and healthy weight loss journey.