Authored: 18/03/2023
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Liraglutide (Generic Saxenda)
Overview
Liraglutide is a prescription weight loss injection that helps regulate appetite and reduce calorie intake. It mimics a natural hormone (GLP-1) to promote fullness and slow digestion.
- Generic version of Saxenda
- Once-daily injection
- Clincally proven for weight loss
Overview
Purchase Liraglutide Weight Loss Pens
You can buy Liraglutide weight loss pens from our UK registered online prescribing service. Liraglutide is the generic version of Saxenda, now available in the UK. It is a daily injection pen, and has been shown to help patients achieve 5-10% body weight loss.
You can order Liraglutide after completing an online assessment with our clinicians. If a prescription is approved, this is passed to our pharmacy team, who prepare and post your treatment.
What Is Liraglutide?
Liraglutide is a UK-licensed weight loss injection designed to help patients reduce their appetite, control cravings, and achieve long-term weight loss. It is a GLP-1 receptor agonist that mimics the body’s natural appetite-regulating hormone.
Marketed as Saxenda for weight management, Liraglutide is available for those with:
- BMI of 30+ (classified as obese)
- BMI of 27+ with a weight-related condition such as high blood pressure, diabetes, or high cholesterol
Liraglutide is also available as Victoza, a lower-dose version used for type 2 diabetes treatment.
How Does Liraglutide Work?
Liraglutide works by mimicking GLP-1, a hormone that helps regulate blood sugar levels and appetite. It promotes weight loss by:
- Reducing hunger: Helps you feel full for longer.
- Slowing digestion: Decreases how quickly food leaves the stomach, reducing calorie intake.
- Controlling cravings: Lowers the urge to snack or eat excessively.
For more information, see the Patient Information Leaflet (PIL).
Eligibility and Contraindications
This treatment may be suitable for adults who:
- Have a BMI of 30 or higher
- Have a BMI of 27+ and suffer from weight-related conditions such as:
- High blood pressure
- High cholesterol
- Type 2 diabetes
- Obstructive sleep apnoea
Who should not use Liraglutide?
Liraglutide is not suitable for:
- Pregnant or breastfeeding women
- People with a history of thyroid cancer or pancreatitis
- Those allergic to liraglutide or its ingredients
Effectiveness of Liraglutide
Clinical trials show that Liraglutide 3 mg (Saxenda) can help patients lose 5-10% of their body weight in 12 months when combined with diet and exercise.
Studies suggest that if a patient does not lose at least 5% of their body weight within 12 weeks, treatment may be discontinued.
Dosage & Administration
Liraglutide is a once-daily injection administered under the skin (subcutaneous). The dose is gradually increased over five weeks:
- Week 1: 0.6 mg per day
- Week 2: 1.2 mg per day
- Week 3: 1.8 mg per day
- Week 4: 2.4 mg per day
- Week 5 onwards: 3 mg per day (full dose)
It should be injected into the abdomen, thigh, or upper arm. View the official Patient Information Leaflet for full instructions.
Alternatives to Liraglutide
If Liraglutide is not suitable, other GLP-1 weight loss injections include:
- Mounjaro (Tirzepatide) - a dual-action GLP-1 and GIP agonist.
- Wegovy (Semaglutide) - a weekly GLP-1 injection.
There are other weight loss treatments available, including:
- Orlistat (Xenical) - a tablet that reduces fat absorption.
Side Effects
Common side effects include:
- Nausea and digestive issues
- Headaches or dizziness
- Injection site reactions
Serious but rare side effects include pancreatitis, gallbladder disease, and thyroid tumours. Seek medical attention if you experience severe stomach pain, yellowing of the skin, or difficulty swallowing.
Written by Qualified Experts
All of our medication and condition content is written by UK qualified pharmacists and doctors.
Reviewed: 18/03/2025
FAQ
General Information
What is Liraglutide and how does it work?
Liraglutide is a GLP‑1 receptor agonist that reduces hunger and improves insulin release by mimicking the natural GLP‑1 hormone.
Is Liraglutide for weight loss or diabetes?
It’s used for both. Generic liraglutide is commonly used for weight loss, while brands like Victoza treat type 2 diabetes.
Is Liraglutide the same as Saxenda?
Yes. Saxenda is the branded version of liraglutide approved for weight loss.
Usage & Dosage
How often do I take generic Liraglutide for weight loss?
It is administered via a daily subcutaneous injection.
How do I inject it?
Inject it under the skin in your stomach, thigh, or upper arm using a pre-filled pen.
What is the dosing schedule for weight loss?
Start at a low dose and gradually increase to the maintenance dose as directed by your doctor.
What should I do if I miss a dose?
Take it as soon as you remember; if more than 12 hours, skip it and resume your schedule.
Can I stop taking Liraglutide once I reach my goal weight?
Stopping may lead to weight regain; long-term use is often recommended.
Effectiveness & Results
How long does it take for Liraglutide to work?
Reduced appetite may be seen within days, with significant weight loss in 3–6 months.
Why might I not be losing weight on Liraglutide?
Ensure you’ve reached the full dose, follow a healthy diet, exercise, and give the treatment time.
What should I eat while taking Liraglutide?
A high-protein, balanced diet supports weight loss and minimizes side effects.
Can I drink alcohol while taking Liraglutide?
Moderate consumption is usually safe, but it may worsen nausea.
Side Effects & Safety
What are the common side effects?
Nausea, diarrhea, constipation, stomach pain, and headaches.
How can I reduce nausea?
Eat small, bland meals, avoid heavy foods, and stay hydrated.
Are there any serious risks?
Rare risks include pancreatitis, gallbladder disease, kidney issues, and thyroid tumors.
Can Liraglutide cause low blood sugar?
Not alone; however, it may increase hypoglycemia risk when used with other diabetes meds.
Storage & Travel
How should I store Liraglutide?
Keep it refrigerated until first use; then store at room temperature below 30°C for up to 30 days.
Can I take it on holiday?
Yes, if you store it properly in an insulated bag with cool packs.
Access & Cost
Can I get Liraglutide on the NHS?
NHS access is limited; it’s often available via specialist weight management programmes.
Do I need a prescription?
Yes, Liraglutide is prescription‑only in the UK, but you can order it online via our weight care service.
Compare
Treatment Comparison
| Saxenda | Xenical | Orlistat | Mysimba | |
| Ingredient | Liraglutide | Orlistat 120mg | Orlistat 120mg | Naltrexone/Bupropion |
| Mechanism | Regulates appetite | Reduces fat absorption | Reduces fat absorption | Regulates appetite |
| Dose | Injected once daily | One three times daily with meals | One three times daily with meals | Gradually increased to 4 tablets daily |
