• Malarone
  • Malarone

Atovaquone/Proguanil (Malarone)

Medication features

  • Anti-malaria tablet
  • Take 1-2 days before entering a malarial zone
  • Take each day you are in the malarial zone
  • Continue for 7 days after leaving the malarial zone


Malarone Tablets Online UK

You can request to buy Malarone online for your trip abroad online, with Simple Online Pharmacy. Whether you are on Safari in Africa, island hopping through Indonesia or seeing Indias rural wonders, Malaria is a threat that should be taken seriously. Malaria is one of the world most lethal diseases and is spread by mosquitoes, present in many tropical and subtropical countries. There is no vaccination, however, malaria tablets are highly effective in preventing malaria.

You can order Malarone or generic Malarone tablets through our registered online doctor service. After completing the online consultation, our doctor will review your assessment and prescribe the selected medication where appropriate. Our pharmacy will then dispense and dispatch your prescription to your door.

What is Malarone?

Malarone is an antimalarial medicine primarily used to prevent or treat malaria. Malaria is caused by an infected mosquito biting a person which can then pass on the malaria parasite P. falciparum into the blood. Entering into a malaria area without the necessary precautions can be dangerous as in 2019 malaria claimed over 400,000 lives.

Malarone is the original branded version of the combination medication, atovaquone, and proguanil. As GSK the makers of Malarone have now lost exclusivity over the manufacture, there are now less expensive versions of Malarone available. Sometimes known as 'generic Malarone’, these options contain exactly the same active ingredient as Malarone and are medically equivalent. These are still manufactured to the highest standards, yet generic Malarone is significantly cheaper than the original branded Malarone.

Visit the Fit For Travel site before completing the online consultation, and find out if Malarone is the antimalarial you need.


In order to be protected from the moment you enter the malaria risk area, you must begin 1-2 days before you travel. For maximum effectiveness, ensure you follow the directions for use closely.

A study on Malarones effectiveness found that it gave over 95% protection for malaria. This can be further improved by using preventative measures such as mosquito nets, insect repellents and wearing long sleeve protective clothing.

How to take Malarone

Malarone and the generic version should be started 1-2 days before entering a malarial zone.

The adult dose is one tablet daily, starting 1-2 days before travelling to the risk area, taking one each day while in the area, and continuing to take one tablet daily for seven days after leaving.

This medicine is preferred by some people due to the need to be taken for only 7 days after returning as opposed to 28 days like the alternatives require.

How it works

Malarone works by killing the parasite that causes Malaria. As you start taking the medication before you enter the malarial zone, there should be high enough levels of the drugs in your body to kill the parasite should be bitten by a carrier mosquito. 

Malarone Price

The price of the branded Malarone is significantly more expensive than atovaquone/proguanil (generic Malarone). Both medications are medically equivalent and contain the same amount of the active ingredient, so unless you have an intolerance to an inactive ingredient in Malarone, most patients elect to use the generic form which is cheaper.

Our Malarone prices are checked weekly, and we always aim to have the cheapest Malarone price online. As we have the lowest price guarantee, we will match any price you find cheaper elsewhere.

Malarone Summary


Take ONE tablet daily2 days before, during, and 7 days after travelling

Type of medicine



Kills the parasite that causes malaria

Active Ingredient

Atovaquone & Proguanil


from £19.20 (generic)

Side Effects

Can include headaches, upset stomach, nausea, diarrhoea

Malarone Alternatives

Other malaria tablets available from our online doctor include 

Malaria Tablet dosage

You should also use bite prevention measures to minimise the risk of bites or contraction of the disease. Using insect repellents containing DEET, wearing long sleeve clothing and using mosquito nets, are all methods of ensuring you are reducing your risk of contracting malaria.

Read more about Malaria or visit the NHS choices website for further information.


What is the dosage of Malarone?

Malarone is taken once daily, starting 1-2 days before entering the malarial zone, and continuing each day, and for 7 days after leaving the malarial zone.

How much is Malarone?

Malarone tablets can vary in price depending on the quantity required. Prices range from £2.25 per tablet to £3.10 per tablet. Generic Malarone is a cheaper, medically equivalent version of Malarone.

How effective is Malarone?

It is important to know, that no anti-malaria tablet offers 100% protection against Malaria. Although the risk is greatly reduced, you should still take measures to protect against bites, such as covering your skin and applying insect repellent.

How long do I need to take Malarone Tablets?

You need to take Malarone / Generic Malarone daily for the length of your stay in a malarial zone, as well as 7 days after leaving, and 1-2 days before entering.

What are the alternatives to Malarone?

Depending on where you are travelling, you may also be able to take Lariam, Doxycycline, or Lariam. The NHS fit for travel website will give information as to which anti-malarial you need.

What is the difference between Malarone and Atovaquone and Proguanil (Generic Malarone)?

Malarone contains the active ingredients Atovaquone 250mg and Proguanil 100mg. Medically there are no differences between Malarone and "Generic Malarone", as they both contain exactly the same amount of active ingredient.

Can I buy Malarone over the counter?

Malarone is a prescription-only medication, so cannot be bought over the counter at a pharmacy. A doctor must assess whether it is suitable for you.

How does Malarone work?

Malarone works by killing the parasite (P. falciparum) which causes Malaria.

Is there a generic version of Malarone?

Yes, the generic form of Malarone is Atovaquone and Proguanil. Atovaquone and Proguanil is the name of the drug which is in the brand Malarone. As long as it is purchased from a reliable source (a registered UK pharmacy) then the doses will be bioequivalent with Malarone.

How many Malarone tablets do I need?

To calculate how many Malarone tablets you need, simply add 9 to the number of days you will be spending in the malarial zone. This accounts for the time spent in the area, 2 tablets before leaving, and 7 for when you arrive back.

Will Malarone affect the contraceptive pill?

No, there is no evidence that this antimalarial medicine will affect the contraceptive pills effectiveness.

Side Effects

Malarone is a well-tolerated medicine, however, as with any medication you take, there is always a risk of side effects occurring. Some are more common than others, and often side effects may subside with the regular usage of the medicine. If the side effects do not subside, you should report them to us, or your GP.

Common Side Effects

  • Headaches
  • Upset stomach
  • Nausea / Vomiting
  • Stomach Pain
  • Diarrhoea
  • Dizziness
  • Itchy rash
  • Insomnia

The side effects listed below are more serious, and you should stop taking Malarone, and report these to your GP immediately.

  • Swollen eyelids, face, and lips. Sign of allergic reaction.
  • Sudden wheezing, tightness of chest.

The side effects listed below are serious, and you should stop taking Malarone, and report these to your GP as a matter of urgency

  • Blistering skin rash
  • Rash, with blistering or peeling skin, particularly around your mouth, nose, eyes or genitals.

For a full list of side effects, please read the patient information leaflet.


Info Leaflet

Before taking any medication, it is important to read the Patient Information Leaflet. You can find information leaflets for your medicines by typing them into the search bar at, or by contacting us.


Warnings and precautions

There may be those who are not suitable for Malarone tablets. When completing your assessment with Simple Online Pharmacy, ensure you provide us with all the information requested for your safety.

Do not take this medicine if:

  • You are pregnant or breastfeeding
  • Are allergic to any listed ingredient
  • Have kidney problems

Other Medicines

Some medicines can interact with Malarone and its generic. It is important that you discuss your suitability further with a doctor if you take warfarin, metoclopramide, tetracycline, rifampicin, rifabutin, HIV treatments or cancer treatments.

Although this medicine can be used to treat malaria, the dose provided is for the prevention of malaria when entering a malaria zone only. If you believe you have malaria and need treatment, seek medical attention immediately.

Order on Monday to Friday until 3:30pm guarantees next day delivery options


Prices From £12.25 / 3 Days (12 tablets)

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Atovaquone/Proguanil (Malarone)

Medication Simple Online Pharmacy
Branded x12 Months (386 Tablets) £859.95
Branded x6 Months (193 tablets) £449.25
Branded x12 Weeks (93 tablets) £218.00
Branded x10 Weeks (79 tablets) £192.95
Branded x9 Weeks (72 tablets) £179.95
Branded x8 Weeks (65 tablets) £157.95
Branded x7 Weeks (58 tablets) £146.95
Branded x6 Weeks (51 tablets) £129.95
Branded x5 Weeks (44 tablets) £113.65
Branded x4 Weeks (37 tablets) £95.75
Branded x3 Weeks (30 tablets) £79.55
Branded x2 Weeks (23 tablets) £63.50
Branded x12 Days (21 Tablets) £59.45
Branded x10 Days (19 tablets) £55.45
Branded x9 Days (18 tablets) £53.65
Branded x8 Days (17 tablets) £51.95
Branded x1 Week (16 tablets) £49.15
Generic x12 Months (386 Tablets) £409.99
Generic x6 Months (193 tablets) £207.99
Generic x12 Weeks (93 tablets) £110.99
Generic x10 Weeks (79 tablets) £102.99
Generic x9 Weeks (72 tablets) £91.99
Generic x8 Weeks (65 tablets) £77.99
Generic x7 Weeks (58 tablets) £69.99
Generic x6 Weeks (51 tablets) £60.99
Generic x5 Weeks (44 tablets) £52.40
Generic x4 Weeks (37 tablets) £43.99
Generic x3 Weeks (30 tablets) £35.99
Generic x2 Weeks (23 tablets) £27.60
Generic x12 Days (21 Tablets) £25.99
Generic x10 Days (19 tablets) £22.10
Generic x9 Days (18 tablets) £21.15
Generic x8 Days (17 tablets) £20.20
Generic x1 Week (16 tablets) £19.20
Branded x3 Days (12 tablets) £36.99
Generic x3 Days (12 tablets) £12.25

Doxycycline 100mg Capsules

Medication Simple Online Pharmacy
212 ( 6 months) £32.50
114 ( 12 weeks) £23.95
86 (8 weeks) £19.45
72 (6 weeks) £18.48
65 (5 weeks) £17.45
58 (4 Weeks) £16.45
51 (3 weeks) £15.45
44 ( 2 weeks) £14.45
37 (1 week) £12.50

Chloroquine Tablets

Medication Simple Online Pharmacy
114 £35.50
62 £21.50
34 £14.50
26 £12.50
22 £10.99
20 £9.99
18 £8.99
16 £7.99
14 £6.99
12 £5.99

Mefloquine | Lariam

Medication Simple Online Pharmacy
12 Week Stay (19 Tablets) £48.95
8 Week Stay (15 Tablets) £37.50
6 Week Stay (13 Tablets) £32.95
5 Week Stay (12 Tablets) £30.50
4 Week Stay (11 Tablets) £28.95
3 Week Stay (10 Tablets) £26.95
2 Week Stay (9 Tablets) £24.95
1 Week Stay (8 Tablets) £22.50