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Naproxen

Naproxen

Overview

Naproxen is a nonsteroidal anti-inflammatory drug (NSAID) used to relieve pain, reduce inflammation, and decrease fever. It's commonly used for conditions such as arthritis, muscle aches, and menstrual cramps.

  • Available as 500mg and 250mg 
  • Non-steroidal anti-inflammatory drug (NSAID)
  • Helps treat conditions such as  muscle pain, arthritis, period pain and gout

Overview

Buy Naproxen 500mg Tablets Online

You can buy Naproxen pain relief treatment online using our UK registered online doctor and pharmacy service. An online consultation in the form of an assessment is required to place an order. This can then be evaluated by our GPs who can make sure it is safe and suitable for you to take.

If approved by our doctors, a prescription is sent to our pharmacy team. It is dispensed and dispatched to your chosen delivery address. We use Royal Mail as a courier and have a range of delivery options.

What Is Naproxen?

Naproxen is a painkiller medicine that specifically targets inflammatory pains. It belongs to a medicine class known as non-steroidal anti-inflammatory drugs (NSAIDs). Other medicines in this category include ibuprofen, aspirin and diclofenac. Typically people find that Naproxen provides more inflammatory pain relief than ibuprofen or aspirin.

Depending on the pain severity, 250mg or 500mg doses are available. The lowest effective dose should be used to minimise the chance of side effects. Pain and inflammation should be noticeably reduced in 30-60 minutes after taking a dose of Naproxen.

It is only available on prescription, although you can buy it over the counter for period pain and menstrual cramps from a pharmacy under the brand name Feminax Ultra.

What Is Naproxen Used For?

It is commonly prescribed for pain relief and to treat inflammation in conditions such as gout, rheumatoid arthritis, sprains and strains and osteoarthritis. Because NSAIDs do not have the potential to cause addiction such as opioid-based painkillers, it is the preferred treatment for those who suffer inflammatory pain. Naproxen (or other NSAIDs) along with paracetamol may make up the base of pain relief treatments before using potentially addictive medicines.

How Does Naproxen Work?

Non-steroidal anti-inflammatories such as Naproxen work by reversibly stopping enzymes in the body responsible for producing an inflammation causing substance known as prostaglandins. Prostaglandins usually signal the body to induce inflammation, by reducing their numbers in the body by slowing their production, inflammation is reduced.

Naproxen, Paracetamol & Other Painkillers

Yes, Naproxen can be taken alongside paracetamol or paracetamol/codeine combinations such as co-codamol. However, it should not be taken with ibuprofen, aspirin, or diclofenac because they are from the same class of medicines (NSAIDs) and will cause increased side effects that may be dangerous.

It is important to note that many other medicines can contain NSAIDs or paracetamol in combination such as cold and flu medicines. This can lead to accidental double doses that can result in side effects. Always ensure you are aware of what is in each medicine you take before use.

As with all pain medicines, it is best to use the lowest effective dose required to avoid the potential side effects of treatments.

Naproxen Dose

You should take it exactly as your doctor has told you to. The dose may vary from person to person depending on why your doctor has prescribed it. The usual Naproxen dosage is to take a dose twice a day with food.

Two strengths are available: Naproxen 250mg and Naproxen 500mg. Your doctor will decide the safest strength and dose for you. Usually, you should take the lowest effective dose for the shortest time. However, some people can be prescribed Naproxen long-term to relieve pain in chronic conditions.

If you have been prescribed Naproxen for a long time, it is important that you are aware of the ways to protect yourself from the potential side effects. Refer to warnings and precautions for more information.

Regular or Gastro-Resistant Naproxen

Naproxen is available as regular tablets or as gastro-resistant tablets. The gastro-resistant tablets have a coating that protects them from stomach acid and releases the drug later on in the gut. This can help to protect the stomach from being irritated by the drug.

Naproxen Summary

Dose

Take ONE tablet ONCE or TWICE daily with food as directed

Type of medicine

NSAID - Non-steroidal anti-inflammatory drug

Mechanism

Reduces prostaglandins in the body which lead to inflammation

Available Strengths

250mg & 500mg

Active Ingredient

Naproxen

Price

From £10.94

Side Effects

Can include stomach upset, dizziness, headache, nausea.

Naproxen Prices

250mg x 28 Tablets

£10.94

250mg x 56 Tablets

£19.98

500mg x 28 Tablets

£11.99

500mg x 56 Tablets

£23.98

250mg x 28 GR Tablets

£13.99

250mg x 56 GR Tablets

£19.50

500mg x 28 GR Tablets

£17.99

500mg x 56 GR Tablets

£25.99

Naproxen Alternatives

For people unable to take this medicine, paracetamol is a suitable alternative as it can be used by most people. Other NSAIDs available over the counter include ibuprofen, aspirin, and topical diclofenac (Voltarol).

A number of other NSAIDs can be prescribed by your doctor if suitable. Examples include celecoxib, ketoprofen, and mefenamic acid.

Naproxen Side Effects

As with all medicines, there is a potential for side effects with Naproxen, although not everyone will get them. Common side effects of Naproxen include headache, dizziness, tiredness, and ringing in the ears. You can find more information on common and less common side effects in the patient information leaflet.

When taking this medicine, there are some serious side effects to be aware of. If you notice any stomach problems like indigestion, nausea, stomach pain or vomiting, it may be a sign of a stomach ulcer. If you notice any of these symptoms, speak to your doctor immediately.

Other side effects to mention to your doctor immediately are if you notice black tarry stools or you vomit blood or particles that look like coffee grounds. If this occurs, stop taking naproxen immediately and seek medical advice.

It is important to read the patient information leaflet for further information regarding the potential side effects of treatment.

Written by Qualified Experts

All of our medication and condition content is written by UK qualified pharmacists and doctors.

FAQ

General Information

Is Naproxen stronger than ibuprofen?

Both Naproxen and ibuprofen are NSAIDs. Naproxen is generally more potent than low‐strength ibuprofen available over the counter, although higher strengths of ibuprofen can be prescribed which are comparable to Naproxen.

Is Naproxen the same as ibuprofen?

No, they are different drugs; however, they belong to the same group of medicines (NSAIDs). Ibuprofen is available over the counter, whereas Naproxen is typically available on prescription (except for period pain formulations).

Effectiveness & Results

How long does Naproxen take to work?

You should notice a beneficial effect approximately 1 hour after taking a dose. For long-term treatment, it may take several days for the full anti-inflammatory effect to be realised.

Side Effects & Safety

Does Naproxen make you drowsy?

Drowsiness is listed as a potential side effect, although it is not common. Unlike codeine-based painkillers, drowsiness is not typically expected. However, avoid driving until you know how Naproxen affects you.

Is Naproxen addictive?

No, Naproxen is not addictive and does not carry the risk of addiction associated with opioid painkillers.

Interactions

Can you drink alcohol with Naproxen?

Yes, you can drink alcohol while taking Naproxen, but excessive alcohol consumption may increase the risk of stomach problems. It is best to drink responsibly or avoid alcohol if possible.

Access & Cost

Can I buy Naproxen over the counter?

Yes, a brand called Feminax Ultra is available over the counter for treating period pain. However, for conditions such as rheumatoid arthritis, Naproxen is typically only available via prescription as Naproxen 500mg tablets.

Can I buy Naproxen online?

In the UK, Naproxen is a prescription‑only medicine (except for specific formulations for period pain). You can request it online from registered online doctors and pharmacy services, such as Simple Online Pharmacy, after completing an online medical assessment.

Reviews

Info Leaflet

Before taking any medication, it is important to read the Patient Information Leaflet: 

Warnings

Naproxen Warnings and Precautions

If prescribed naproxen long term, it is important that you are aware of how to protect the stomach while using the medicine. Food should always be consumed before having a dose to protect the stomach from the effect of naproxen. Your doctor may decide to prescribe you a treatment to lower the stomach acid to help further.

Other conditions and Naproxen

It is not suitable for everyone to take. People who have had an allergic reaction to Naproxen or another NSAID should not take it. This includes people with asthma who have found their asthma worsened after taking an NSAID. 

People with a history of stomach ulcers or gastrointestinal diseases like Crohn’s or ulcerative colitis should not take Naproxen. People with severe liver, kidney, or heart failure are not able to take Naproxen. For a full list of conditions that can be affected by this medicine, see the patient information leaflet. If you are unsure, talk to your doctor or pharmacist for advice.

Interactions with other medicines

Naproxen can interact with a wide variety of medicines. Examples include blood-thinning medicines like warfarin, diuretics, and certain blood pressure medicines. It should also not be taken with other NSAIDs such as aspirin or ibuprofen. This includes low dose aspirin that people are often prescribed after a heart attack or stroke.

Interactions between Naproxen and other medicines can be dangerous and you should check with your doctor if you start any new medication whilst taking this medicine.

Naproxen in pregnancy and breastfeeding

Naproxen should not be used within the first 6 months of pregnancy without consultation with a doctor who can assess the risk versus benefit of the treatment. It should NOT be used at all within the last 3 months of pregnancy as it can result in serious complications.

Naproxen does pass into the breastmilk in small amounts. Due to this, it is not recommended to use naproxen during breastfeeding without direct instruction from a doctor.

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Tyson Wilkman
Tyson Wilkman
Clinical Pharmacist
AHPRA Registration: PHA0002235589