• Naproxen
  • Naproxen


Medication features

  • Used for effective pain relief
  • Gastro resistant version available
  • Belongs to class of drugs called  non-steroidal anti-inflammatory drugs (NSAIDs)
  • Helps treat conditions such as  muscle pain, arthritis, period pain and gout


Order Naproxen Tablets Online

You can request to order Naproxen tablets using our UK registered online doctor and pharmacy service. This service is only available to patients who are currently prescribed Naproxen on repeat by their own GP. As part of your order, we ask that you complete an online medical assessment. This can then be evaluated by our GPs who can make sure it is safe and suitable for you to take.

If approved by our doctors, a prescription is sent to our pharmacy team. From here, it is dispensed and dispatched to your chosen delivery address. We use Royal Mail as a courier and have a range of delivery options.

What is Naproxen?

It is an anti-inflammatory painkiller used to treat pain and inflammation in several conditions. Naproxen is a non-steroidal anti-inflammatory drug (NSAID). Other medicines in this category include ibuprofen and aspirin.

It is only available on prescription, although you can buy it for period pain and menstrual cramps from a pharmacy under the brand name Feminax Ultra.

What is Naproxen used for?

It is commonly prescribed for pain relief and to treat inflammation in conditions such as gout, rheumatoid arthritis, sprains and strains and osteoarthritis. Unlike some other painkillers, taking it does not have a risk of addiction.

Can I take Paracetamol or Co-codamol with Naproxen?

Yes, Naproxen can be taken alongside paracetamol or co-codamol. However, it should not be taken with ibuprofen, aspirin, or any other NSAID such as diclofenac because it can cause dangerous side effects.

How do I take Naproxen?

You should take it exactly as your doctor has told you to. The dose may vary from person to person depending on why your doctor has prescribed it. The usual Naproxen dosage is to take a dose twice a day.

Two strengths are available: Naproxen 250mg and Naproxen 500mg. Your doctor will decide the safest strength and dose for you. Usually, you should take the lowest effective dose for the shortest time. However, some people can be prescribed Naproxen long-term to relieve pain in chronic conditions.

Regular or gastro-resistant Naproxen

It is available as regular tablets or as gastro-resistant tablets. The gastro-resistant tablets have a coating which protects them from stomach acid and releases the drug later on in the gut. This can help to protect the stomach from being irritated by the drug.

Naproxen Summary

Naproxen Dosing

Take 250-500mg once or twice daily as directed.


Lowers inflammation by reducing prostaglandins responsible for inflammation.


From £10.99

Side effects

Can include stomach upset, dizziness, headache, nausea.

Naproxen Prices

Naproxen 250mg x 28 tablets


Naproxen 250mg x 56 tablets


Naproxen 500mg x 28 tablets


Naproxen 500mg x 56 tablets


Naproxen Alternatives

For people unable to take this medicine, paracetamol is a good alternative because it is suitable for most people. Other NSAIDs available over the counter include ibuprofen, aspirin, and topical diclofenac (Voltarol).

A number of other NSAIDs can be prescribed by your doctor if suitable. Examples include celecoxib, ketoprofen, and mefenamic acid.


Is Naproxen stronger than ibuprofen?

Both of these medicines are similar drugs and both are types of NSAIDs. Naproxen is generally more potent than low strength ibuprofen that you can get over the counter. However, doctors are able to prescribe higher strengths of ibuprofen which are similar to Naproxen. Both drugs can generally be used as first choice NSAIDs because they have fewer side effects than some other NSAIDs.

Does Naproxen make you drowsy?

Drowsiness is listed as a common side effect. This means that up to 1 in 10 people can experience drowsiness as a side effect.

Can I buy Naproxen over the counter?

A brand called Feminax Ultra is available over the counter to treat period pain. However, when used for other conditions such as rheumatoid arthritis, it is only available with a prescription.
It is available in a 250 mg strength and a 500 mg strength.

Can you drink alcohol with Naproxen?

You can drink alcohol while taking it but it can increase the risk of stomach problems if you drink too much alcohol with it.

Is Naproxen the same as ibuprofen?

It is a different drug to ibuprofen. However, they belong to the same group of medicines called nonsteroidal anti-inflammatory drugs (NSAIDs). Ibuprofen can be bought over the counter whereas Naproxen is a prescription-only medicine (except when used for period pain). Both are anti-inflammatory painkillers.

Is Naproxen addictive?

It is not an addictive drug and does not carry the same risk of addiction as painkillers like codeine and morphine.

How long does Naproxen take to work?

You should notice a beneficial effect around 1 hour after taking a dose. However, if you are taking it long-term it can take a number of days for Naproxen to work and have the full anti-inflammatory effect.

Can I buy Naproxen online?

Naproxen, in the UK, is a prescription-only medicine. You can request to order it from certain registered online doctor and pharmacy services such as Simple Online Pharmacy. It is not suitable for everyone and to use this service you must already be prescribed it by your own GP.
We ask that you complete an online medical assessment as part of your order. This can be reviewed by our doctors who can check whether it is safe and suitable for you to take. If approved by our doctors, a prescription is sent to our pharmacy team. From here, it is dispensed and dispatched to your chosen delivery address.

Side Effects

Naproxen Side Effects

Common side effects of Naproxen include headache, dizziness, tiredness, and ringing in the ears. You can find more information on common and less common side effects in the patient information leaflet

When taking this medicine, there are some serious side effects to be aware of. If you notice any stomach problems like indigestion, nausea, stomach pain or vomiting, it may be a sign of a stomach ulcer. If you notice any of these symptoms, speak to your doctor immediately.

Other side effects to mention to your doctor immediately are if you notice black tarry stools or you vomit particles that look like coffee grounds.

This is not a complete list of side effects, it’s important to read the patient information leaflet for further information. 


Info Leaflet

Before taking any medication, it is important to read the Patient Information Leaflet: 


Naproxen Warnings and Precautions

Other conditions and Naproxen

It is not suitable for everyone to take. People who have had an allergic reaction to Naproxen or another NSAID should not take it. This includes people with asthma who have found their asthma worsen after taking an NSAID. 

People with a history of stomach ulcers or gastrointestinal diseases like Crohn’s or ulcerative colitis should not take Naproxen. People with severe liver, kidney, or heart failure are not able to take Naproxen. For a full list of conditions that can be affected by this medicine, see the patient information leaflet. If you are unsure, talk to your doctor or pharmacist for advice.

Interactions with other medicines

Naproxen can interact with a wide variety of medicines. Examples include blood-thinning medicines like warfarin, diuretics, and certain blood pressure medicines. It should also not be taken with other NSAIDs such as aspirin or ibuprofen. This includes low dose aspirin that people are often prescribed after a heart attack or stroke.

Interactions between Naproxen and other medicines can be dangerous and you should check with your doctor if you start any new medication whilst taking this medicine.

Order within for guaranteed next day delivery options


Prices From £10.99 / 28 x 250mg Tablets

Compare Prices
The variation selected is currently out of stock.
Item added to bag. Click here to view bag.
Please select a size from above to proceed.
There are NHS prescriptions in your basket. Please complete the order first or remove NHS prescriptions from the basket.


Medication Simple Online Pharmacy
250mg x28 x 250mg Tablets £10.99
250mg x56 x 250mg Tablets £23.99
500mg x28 x 500mg Tablets £11.99
500mg x56 x 500mg Tablets £28.99
250mg x28 x 250mg GR Tablets £13.99
250mg x56 x 250mg GR Tablets £19.50
500mg x28 x 500mg GR Tablets £17.99
500mg x56 x 500mg GR Tablets £25.99