Authored: 22/01/2021

You can order Varenicline (formerly branded as Champix) from our UK registered online pharmacy and doctor service. While Champix has been discontinued in the UK, generic Varenicline contains the same active ingredient and is equally effective at helping people quit smoking.
After completing an online assessment, our UK-registered GPs will review your suitability for treatment. If approved, your prescription will be passed to our pharmacy team for dispensing and dispatch, with next-day delivery available.
Treatment course | 12 week treatment course |
Mechanism | Reduces nicotine cravings and withdrawal symptoms |
Active ingredient | Varenicline |
Effectiveness | 3x more likely to quit vs no treatment |
Side effects | Nausea, sleep problems, headaches, abnormal dreams |
Success rate | 44% quit rate at 12 weeks |
Varenicline is a prescription-only medication specifically designed to help people quit smoking. It was originally marketed under the brand name Champix but is now available as a generic medication in the UK. It works differently from nicotine replacement therapy (NRT) as it doesn't contain any nicotine.
The medication is particularly effective when combined with behavioral support and a strong commitment to quit smoking. Clinical studies have shown it to be one of the most effective stop-smoking treatments available.
Varenicline works through a dual mechanism of action:
This unique mechanism helps to:
Clinical studies have shown that Varenicline is one of the most effective stop-smoking treatments available:
Success rates are highest when Varenicline is combined with:
Varenicline follows a structured 12-week treatment course:
Period | Dosage | Notes |
---|---|---|
Days 1-3 | 0.5mg once daily | Initial starting dose |
Days 4-7 | 0.5mg twice daily | Morning and evening |
Week 2-12 | 1mg twice daily | Maintenance dose |
Key points for taking Varenicline:
Common side effects of Varenicline include:
Most side effects are mild to moderate and often improve as your body adjusts to the medication. Contact your doctor if side effects are severe or persistent.
Several alternatives to Varenicline are available:
All of our medication and condition content is written by UK qualified pharmacists and doctors.
Authored: 22/01/2021
Reviewed: 27/01/2025
There can be side effects when taking the tablets. As with any medicine, some side effects are common while others are rarer. Common side effects include sinusitis, decreased or increased appetite, abnormal dreams, headaches, dry mouth.
Less commonly, it can cause serious serious psychiatric side effects. If you notice symptoms such as an agitated, depressed mood or other mood changes, seek advice from a healthcare professional immediately.
Read the patient information leaflet for further information on the possible side effects of Champix.
Before buying or taking Champix – it is important you read the Patient Information Leaflet (PIL)