• Tadalafil
  • Tadalafil
  • Tadalafil
  • Tadalafil


Medication features

  • The generic version of Cialis
  • Effective for up to 72 hours
  • Takes about 30 minutes to take effect


Order Tadalafil Tablets Online

You can request to buy Tadalafil tablets online in the UK, from our UK registered online pharmacy and doctor service. After completing your assessment and checking out, your order will be passed to our UK registered doctors for review. If approved, our pharmacy team will dispense and dispatch your medication to your chosen address.

Tadalafil, also known as generic Cialis, is a treatment for erectile dysfunction. This is the drug in the well known ED medication Cialis. Generic Tadalafil became legally available in the UK on November 14th, 2017. Before this date, the drug was only available in the well known branded medication, Cialis. Generic versions of drugs are often much more affordable than the original brands. 

We have checked our prices against our competitors and are amongst the cheapest online for all treatments. There are no prescription fees and no delivery charges on orders over £35.

About Tadalafil

Cialis and Generic Cialis

Tadalafil is the active ingredient in the well known erectile dysfunction drug Cialis. As of 2017, Cialis no longer has an exclusive patent on this drug, and this means that other companies are able to manufacture Tadalafil.

While medically the same, the competition means prices for generic medicines are cheaper than the original versions. By using the price comparison button, you can see that Tadalafil is significantly cheaper than Cialis. While some men still prefer the branded version, many others have switched to using Tadalafil.

Cialis vs Tadalafil

What does Tadalafil do?

It is a drug used to treat erectile dysfunction in men. It does this by improving blood flow to the penis when sexually stimulated. This allows men who suffer from ED to achieve firmer and longer-lasting erections. 

Why Tadalafil?

With a number of ED drugs available, many men are unsure which medication is right for them. The main advantage of Tadalafil over Sildenafil, Viagra, Levitra, and Spedra, is the length of action. 

What does this mean? Basically, the effects of Tadalafil can last for up to 72 hours after taking a dose. It should be noted, this does not mean that your erection will last this long! In fact, any erection which is painful or lasts more than 4 hours should be brought to the attention of your doctor immediately. The 72-hour effect simply means that you should be able to achieve an erection when sexually stimulated, in the 3 days after taking the pill.

Daily Dosing

If a 10mg or 20mg dosage is successful in treating your ED, you may wish to consider using the 2.5mg or 5mg daily dose. The reason men may use this daily dose is that it maintains levels of Tadalafil in the blood all the time. This means you do not need to remember to take it each time you wish to have sex. Simply take the daily tablet each day, and this should mean you can achieve an erection, whenever you come to engage in sexual activity.

The convenience of not needing to take your medication with you everywhere, and simply taking it with your breakfast each morning, is a change in how traditional ED medications have worked.

The Alternatives

Of course, Tadalafil is not the only treatment option for sufferers of erectile dysfunction. You may wish to choose other drugs to treat your ED, or even try a drug-free approach.

Depending on the cause of your erectile dysfunction, it is possible that you could resolve your symptoms without taking any medication. For example, alcohol can be a cause of ED, and if your intake is high, you can try reducing your weekly intake to see if this helps. If you are overweight, you may also find trouble getting and maintaining an erection. Losing weight can improve erectile dysfunction.

Counselling can also be helpful if anxiety and stress play a role in your symptoms.

In terms of other ED medicines available, the branded version of Tadalafil, Cialis is an option. Viagra and Sildenafil are also alternatives, and while they do not provide as long lasting an effect, they are very effective ED treatments. Levitra and Spedra are the other ED treatments available in the UK, which also have some advantages depending on the patient. Whether you choose a branded drug or one of the generic medicines, check you are ordering from a trusted source. 

Tadalafil Reviews

Some people may be worried when switching from Cialis to Tadalafil, that the generic form of the drug will not work as well. Many of our patients review the medications they purchase from the site. Just click on the "Reviews" tab, to see how other people have found using Tadalafil.

Tadalafil Summary

Tadalafil Dosing

10mg / 20mg You should take ONE tablet 30 minutes before sex. 

Never take more than ONE tablet within 36 hours

2.5mg / 5mg You should take ONE tablet DAILY

Although Tadalafil can be taken with food, this may slow down the time it takes for the drug to work.


Tadalafil is part of the group of pde5 inhibitors, which work by improving and increasing the flow of blood into your penis. This results in a firmer and longer-lasting erection.


Over 80% of men will notice a firmer and longer-lasting erection.

If Tadalafil doesn’t work for you the first time around, it could nevertheless be more effective next time. Doctors often advise trying all erectile dysfunction medicines eight times before giving up.

Side effects

Can include nausea, vomiting, and diarrhoea. Tadalafil can also cause nasal congestion, headaches, facial flushing, slight vertigo, a pounding heartbeat, and blurred vision.

Nitrates and Tadalafil

You should NOT take Tadalafil if taking nicorandil or nitrate-based medication for angina. Please see your GP for treatment options.

Alpha-blockers and Tadalafil

If you are taking alpha-blocking medicines, such as tamsulosin or prazosin, you are advised to leave at least six hours between taking your alpha-blocker and Tadalafil.

Tadalafil Prices

Tadalafil - 4 tablets

from £8.95

Tadalafil - 8 tablets

from £15.95

Tadalafil - 12 tablets

from £22.95

Tadalafil - 16 tablets

from £25.45

Tadalafil - 32 tablets

from £43.95

Tadalafil - 64 tablets

from £84.95

Daily Dose Tadalafil

from £19.85


How do you take Tadalafil?

If taking a 10 or 20mg dose, take one tablet about half an hour before sex. The 2.5mg and 5mg strength are a daily tablet and should be taken at the same time each day. 

How effective is Tadalafil?

The majority of men who take it (around 85%), will notice a firmer and longer-lasting erection. 

How does Tadalafil work?

It enhances the erectile response in men by relaxing smooth muscle and increasing blood flow. It is one of a class of drugs known as PDE-5 inhibitors.

How long does Tadalafil last?

The effects generally last between 24-36 hours. You will only notice an erection however if you are sexually stimulated. Erections which are painful or last longer than 4 hours require medical attention.

How long does Tadalafil take to work?

It can work as soon as 15 minutes after taking. However, you should take it about 30 minutes before sexual activity.

What are the side effects of Tadalafil?

Although uncommon, side effects can include nausea, vomiting, and diarrhoea. It may also result in nasal congestion, headaches, a pounding heartbeat, facial flushing, slight vertigo and blurred vision.

Can I take Tadalafil with Nitrates?

No. A dangerous reaction exists between all ED medication and Nitrates. Tadalafil cannot be prescribed by our doctor if you are taking Nicorandil or nitrate-based medication, such as a GTN spray or isosorbide mononitrate tablets for angina. It can also be dangerous if taken with certain recreational drugs such as ‘poppers’.

Can I take Tadalafil with Alpha-Blockers?

If you are taking alpha-blocking medicines, such as tamsulosin or trazodone, you are advised to wait for at least six hours between taking Tadalafil.

Where can I buy Tadalafil?

You can buy Tadalafil from our online pharmacy after completing an online assessment for your suitability for this medication. It is a prescription-only medicine and requires a doctor to issue a prescription if deemed suitable.

Can I take 20mg of Tadalafil?

Yes. While the starting dose of Tadalafil is generally 10mg, in men who do not get a response to this dosage, the 20mg strength can be prescribed.

Do you need a prescription to buy Tadalafil?

Yes. Tadalafil is a prescription-only medication, so a doctor must issue a prescription in order to dispense this medication. Our UK online doctor can issue a prescription if you complete an assessment, and it is judged that the medication is suitable for you. This prescription is then passed to the pharmacy for preparation.

What is the price of Tadalafil?

Tadalafil starts from £11.25 per box but can become as cheap as 80p per tablet depending on the strength.

Is Tadalafil legal in the UK?

Yes. Tadalafil is a legal drug, prescribable by GMC registered doctors. Only pharmacies can legally distribute the medication, however. If you were offered Tadalafil from another source, this would not be legal as there would be no prescription issued for the use of the drug. The authenticity of the medicine would also be doubtful so, if buying online, it's important you check the registration status of the pharmacy.

Can I buy Tadalafil over the counter?

No. Tadalafil, in the UK, is a prescription-only medication, meaning you will have to have a doctor prescribe you this medication. Unlike Viagra Connect, which became an over-the-counter treatment for ED in 2017, no such license exists for Tadalafil to be sold in this way. A consultation with your GP face to face, or online, will be required to be prescribed the treatment.

Can I buy Tadalafil online?

Yes. You can use a UK registered online pharmacy and doctor service, to buy Tadalafil online in the UK. You should check the service is registered, before buying any medications online. Any online pharmacy and doctor service operating legally in the UK will be registered and overseen by at least 3 bodies. The MHRA, the general pharmaceutical council, and one of either the CQC (Care Quality Commission) or HIS (Health Improvement Scotland). 

What is the difference between Sildenafil and Tadalafil?

While both drugs are from the same class of drug, the main difference is that Tadalafil is longer acting. However, Sildenafil is still slightly cheaper.

Cialis vs Viagra

Is Tadalafil available on the NHS?

There are specific criteria for prescribing Tadalafil and other erectile dysfunction treatments on the NHS. There are a number of conditions which mean you can be prescribed ED treatment by your GP on the NHS. These include men who suffer from Parkinson's, diabetes and some types of cancer. You should speak to your GP for further information if you think you may be eligible for NHS treatment.

What is the difference between Cialis and Tadalafil?

Cialis and Tadalafil contain the same active ingredient (Tadalafil). Cialis is the original branded version of the drug. In November 2017, generic Tadalafil became available, which can be a more affordable option for many. So there is no medical difference between the two medications. 
You will likely notice that their appearances differ in terms of pill type and packaging, however, this is as far as the differences go. When you take the tablet, there should be no difference in effect.

Cialis vs Tadalafil




  • Tadalafil is "Generic Cialis"
  • Items over £35 include free delivery
When Required Dose4 tablets8 tablets16 tablets32 tablets
Tadalafil 10mg£10.95£18.95£34.95£65.95
Tadalafil 20mg£11.95£21.95£36.95£73.95
Cialis 10mg£37.95£68.65£132.00£234.95
Cialis 20mg£38.95£71.95£137.95£239.95
Daily Dose28 tablets56 tablets 84 tablets 
Tadalafil 2.5mg£25.95£45.25 £68.05 
Tadalafil 5mg£28.75£55.75 £74.95 
Cialis 2.5mg£68.95£137.95£189.95 
Cialis 5mg£71.95£142.50£137.95 

Other Clinic Prices

NOTE: Prices correct as of 27th May 2019

Tadalafil 10mg x 4£11.25£19.99£25.00£25.00
Tadalafil 10mg x 8£19.99£29.99£42.00£40.00
Tadalafil 10mg x 16£35.99£49.99£76.00£70.00
Tadalafil 20mg x 4£12.10£19.99£28.00£25.00
Tadalafil 20mg x 8£22.25£29.99£50.00£40.00
Tadalafil 20mg x 16£37.99£49.99£85.00£70.00

* Free Delivery over £35.00

** Delivery Included

*** Additional Delivery Fees Apply

Treatment Comparison

Active IngredientSildenafilSildenafilTadalafilTadalafilVardenafilVardenafilAvanafil
Time to Take Effect30-60 mins30-60 mins15-45 mins15-45 mins30-60 mins30-60 mins15-30 mins
Duration of Action4-6 hours4-6 hours24-36 hours24-36 hours4-6 hours4-6 hours4-6 hours
Unique FeatureSame active ingredient as ViagraMost well knownSame active ingredient as CialisLongest ActingUsed for diabeticsUsed for diabeticsQuickest Acting
Price Per TabletFrom 86pFrom £4.84From 67pFrom £2.26From £2.74From £2.97From £2.97

Side Effects

Side Effects of Tadalafil

With any medication you take, there is always a risk of side effects occurring. Some are more common than others, and often side effects may subside with the regular usage of the medicine. If the side effects do not subside, you should report them to us, your doctor or pharmacist.

Common Tadalafil Side Effects:

  • Headaches
  • Flushing
  • Runny/stuffy nose
  • Upset stomach
  • Nausea
  • Red and/or warm skin
  • Dizziness
  • Nosebleeds
  • Muscle pain / Back Pain

The side effects listed below are more serious, and you should stop taking Tadalafil, and report these to your doctor immediately.

  • An erection that will not go away (priapism). If you have an erection that lasts more than 4 hours, seek medical help immediately. Priapism can permanently damage your penis.
  • Sudden vision loss in one or both eyes. Sudden vision loss in one or both eyes can be a sign of a serious eye problem called non-arteritic anterior ischemic optic neuropathy (NAION). 
  • Sudden hearing decrease or hearing loss. Some people may also have ringing in their ears (tinnitus) or dizziness. 

For a full list of side effects, please read the patient information leaflet.


Info Leaflet

To read the information leaflet for Tadalafil, please visit medicines.org.uk or click the link below


Tadalafil Dosage

Tadalafil 20mg and 10mg tablets - These are 'when required' doses, so should be taken around 30 minutes before sexual activity. 20mg is the maximum allowable dose. If you have found that this dose is not effective for you, it may be that this medicine is not for you. Speak to your GP for further options. If you have liver problems, speak to your GP before taking this because the dose may need to be reduced.

Tadalafil Daily - 2.5mg and 5mg - These are designed as daily dosages. You should take one tablet daily to help maintain the levels of Tadalafil in the bloodstream. 


If you notice your erections are lasting too long, or you are not achieving an erection for long enough, you can adjust your dosage as appropriate. Remember; if taking Tadalafil daily, the maximum dosage is 5mg. If taking Tadalafil when required, the maximum dosage in a 72 hour period is 20mg as a single dose. You may find that to solve your ED issues you only need to take a 5mg tablet every 2-3 days.

Every patient is different, so you should adjust your dose according to the results. It is better to take as little medicine as possible, as this reduces the chances of potential side effects. If you are able to configure your dosage effectively, this will also save you money!

Tadalafil 2.5mg

Cialis 2.5mg

 The daily dosage used when 5mg is too strong


 Tadalafil Daily

Cialis 5mg

Tablet preferred if Tadalafil is established to be effective and the patient prefers daily rather than when required dosing


 Tadalafil 10mg

Cialis 10mg

Common starting dose. Used only just prior to sexual activity.  

 Tadalafil 20mg

Cialis 20mg

Also used just prior to sexual activity. Usually used when 10mg is ineffective.

Order within for guaranteed next day delivery options


Prices From £8.95
As low as £0.67 / Tablet

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Medication Simple Online Pharmacy MedExpress
Assured Pharmacy
10mg Dispersible x32 £199.95
10mg Dispersible x24 £159.95
10mg Dispersible x16 £114.50
10mg Dispersible x8 £59.95
10mg Dispersible x4 £40.95
20mg x32 £219.95
20mg x24 £169.99
20mg x16 £115.50
£169.99 £169.99
20mg x8 £60.95
£89.99 £99.99
20mg x4 £31.95
£46.99 £55.00
10mg x32 £169.95
10mg x24 £124.50
10mg x16 £89.99
£132.99 £119.99
10mg x8 £49.99
£69.99 £60.00
10mg x4 £29.65
£42.99 £43.99
5mg x32 £94.95
5mg x24 £83.95
5mg x16 £67.95
5mg x8 £45.65
£62.99 £59.99
5mg x4 £23.45
£36.99 £37.00


Medication Simple Online Pharmacy MedExpress
Assured Pharmacy
200mg x32 £184.95
£269.99 N/A
200mg x16 £99.50
£134.99 N/A
200mg x12 £76.95
200mg x8 £57.95
£69.99 N/A
200mg x4 £29.95
£36.99 N/A
100mg x32 £134.95
£199.99 N/A
100mg x16 £74.50
£99.99 N/A
100mg x12 £57.95
100mg x8 £39.50
£54.99 N/A
100mg x4 £20.95
£28.99 N/A
50mg x32 £94.95
£169.99 N/A
50mg x16 £49.99
£89.99 N/A
50mg x12 £39.95
50mg x8 £29.95
£49.99 N/A
50mg x4 £19.99
£24.99 N/A


Medication Simple Online Pharmacy MedExpress
Assured Pharmacy
100mg x64 £91.99
£139.99 £127.99
100mg x48 £69.99
100mg x32 £49.95
£89.99 £71.99
100mg x24 £39.99
£69.99 N/A
100mg x16 £25.99
£49.99 £47.99
100mg x12 £22.99
100mg x8 £15.24
£29.99 £29.99
100mg x4 £8.19
£19.99 £16.00
50mg x64 £64.94
£139.99 £127.99
50mg x48 £58.99
50mg x32 £47.99
£89.99 £71.99
50mg x24 £38.99
£69.99 N/A
50mg x16 £24.99
£49.99 £47.99
50mg x12 £19.99
50mg x8 £13.89
£29.99 £29.99
50mg x4 £7.49
£19.99 £16.00
25mg x64 £49.89
£89.99 £96.00
25mg x48 £40.95
25mg x32 £32.49
£79.99 £71.99
25mg x24 £24.95
£69.99 N/A
25mg x16 £17.19
£49.99 £47.99
25mg x12 £14.95
25mg x8 £9.49
£29.99 £29.99
25mg x4 £5.89
£15.99 £16.00
25mg x2 £3.75
50mg x2 £4.25
100mg x2 £4.75

Viagra UK

Medication Simple Online Pharmacy MedExpress
Assured Pharmacy
100mg x64 £449.95
£499.99 £539.99
100mg x32 £235.95
£249.99 £289.99
100mg x16 £121.50
£139.99 £149.99
100mg x12 £95.95
100mg x8 £63.95
£69.99 £79.99
100mg x4 £33.50
£34.99 £47.00
50mg x64 £399.95
£479.99 £519.99
50mg x32 £209.95
£235.99 £285.99
50mg x16 £112.00
£139.99 £149.99
50mg x12 £89.99
50mg x8 £58.95
£69.99 £76.99
50mg x4 £29.95
£34.99 £46.00
25mg x64 £309.95
£439.99 £419.99
25mg x32 £159.95
£219.99 £219.99
25mg x16 £81.95
£119.99 £129.99
25mg x12 £61.95
25mg x8 £43.95
£59.99 £69.90
25mg x4 £24.95
£29.99 £45.00


Medication Simple Online Pharmacy MedExpress
Assured Pharmacy
10mg (When Required Dose) x4 £8.95
£19.99 £19.98
10mg (When Required Dose) x8 £15.95
£29.99 £34.98
10mg (When Required Dose) x12 £22.95
£39.99 £49.99
10mg (When Required Dose) x16 £25.45
£49.99 £59.50
10mg (When Required Dose) x32 £43.95
£89.99 £89.50
10mg (When Required Dose) x64 £84.95
£139.99 £139.98
20mg (When Required Dose) x4 £9.75
£19.99 £19.98
20mg (When Required Dose) x8 £15.95
£29.99 £34.98
20mg (When Required Dose) x12 £23.80
N/A £49.99
20mg (When Required Dose) x16 £28.45
£49.99 £59.50
20mg (When Required Dose) x32 £53.95
£89.99 £89.50
20mg (When Required Dose) x64 £99.95
£139.99 £139.98
5mg (Daily Dose) x28 £22.85
5mg (Daily Dose) x56 £44.85
5mg (Daily Dose) x84 £66.95
2.5mg (Daily Dose) x28 £19.85
2.5mg (Daily Dose) x56 £38.50
2.5mg (Daily Dose) x84 £56.50

Viagra Connect (Sildenafil) 50mg

Medication Simple Online Pharmacy MedExpress
50mg x4 £18.48
£17.99 £19.99 £19.99
50mg x8 £31.98
£33.99 £34.99 £34.99
50mg x12 £49.98
£50.99 £51.99 £50.99
50mg x16 £63.50
£67.99 N/A N/A
50mg x32 £109.95
£139.99 N/A N/A
50mg x2 £10.75


Medication Simple Online Pharmacy
20mg x32 £197.95
20mg x24 £150.95
20mg x16 £103.95
20mg x8 £52.95
20mg x4 £29.95
10mg x32 £133.95
10mg x24 £102.95
10mg x16 £80.95
10mg x8 £44.95
10mg x4 £25.95
5mg x32 £87.75
5mg x24 £77.75
5mg x16 £62.95
5mg x8 £36.65
5mg x4 £17.99

Vitaros Cream

Medication Simple Online Pharmacy
3mg/g x4 Sachets £61.25
3mg/g x8 Sachets £108.99
3mg/g x12 Sachets £153.99


Medication Simple Online Pharmacy MedExpress
Assured Pharmacy
20mg (When Required Dose) x64 £449.95
20mg (When Required Dose) x32 £239.95
£299.99 £260.00
20mg (When Required Dose) x16 £137.95
£139.99 £150.00
20mg (When Required Dose) x12 £109.95
£119.99 £112.00
20mg (When Required Dose) x8 £71.95
£79.99 £84.00
20mg (When Required Dose) x4 £38.95
£39.99 £45.00
10mg (When Required Dose) x64 £444.95
10mg (When Required Dose) x32 £234.95
£299.99 £260.00
10mg (When Required Dose) x16 £132.00
£159.99 £150.00
10mg (When Required Dose) x12 £104.95
£119.99 £112.00
10mg (When Required Dose) x8 £68.65
£79.99 £84.00
10mg (When Required Dose) x4 £37.95
£39.99 £45.00
5mg (Daily Tablet) x84 £189.95
£199.99 £198.00
5mg (Daily Tablet) x56 £142.50
£139.99 £149.99
5mg (Daily Tablet) x28 £71.95
£69.99 £90.00
2.5mg (Daily Tablet) x84 £189.95
£199.99 £198.00
2.5mg (Daily Tablet) x56 £137.95
£149.99 £139.99
2.5mg (Daily Tablet) x28 £68.95
£69.99 £90.00


Medication Simple Online Pharmacy
Sildenafil is Licensed UK alternative x1 £0.00


Medication Simple Online Pharmacy
Sildenafil is Licensed UK alternative x1 £0.00

ED Trial Pack

Medication Simple Online Pharmacy
Sildenafil 50mg x 4, Tadalafil 10mg x 4, Vardenafil 10mg x 4 £42.39