• Spedra


Medication features

  • Works within 15-30 minutes
  • Can work for up to 6 hours
  • Contains Avanafil


Spedra Online

You can request to buy Spedra tablets for erectile dysfunction online, from our UK registered online pharmacy and doctor service. After completing your assessment and checking out, your order will be passed to our UK registered doctors for review. If approved, our pharmacy team will dispense and dispatch your medication to your chosen address.

While not as well known as it's cousins in the ED treatment family, Viagra, and Cialis, Spedra is the fastest acting erectile dysfunction medication. You can review some of Spedra's features in the table below.

Taking Spedra

Take one tablet about 30 minutes before sex.  The effects of Spedra can sometimes be noticed as soon as after 15 minutes, and last 4-6 hours.

Never take more than a 200mg tablet within 24 hours

Although Spedra can be taken with food, this may slow down the time it takes for the drug to work.

How it works

Spedra works by increasing blood flow into the erectile tissue of the penis. Spedra does not have an impact on libido, only your ability to get and maintain an erection when sexually aroused.


Most men will notice a firmer and longer-lasting erection. If the treatment does not work, ask our doctors (or your own GP), whether it would be appropriate to increase the dose. Alternatively, they may recommend another treatment.

If Spedra doesn’t work for you first time around, it could nevertheless be more effective next time. Doctors often advise trying all erectile dysfunction medicines eight times before giving up.

Side effects

While side effects are uncommon, they can include nausea, vomiting, and diarrhoea. Spedra can also cause nasal congestion, headaches, facial flushing, slight vertigo, a pounding heartbeat, and blurred vision.

Nitrates and Spedra

Spedra cannot be prescribed by our doctor if you are taking nicorandil or nitrate-based medication, such as GTN spray or isosorbide mononitrate tablets for angina.

Alpha-blockers and Spedra

If you are taking alpha-blocking medicines, such as tamsulosin or trazodone, you are advised to leave at least six hours between taking your alpha-blocker and Spedra.


  • What is Spedra?

    Spedra is a drug used in the treatment of erectile dysfunction in men.

  • How Does Spedra Work?

    Spedra is a class of drug (like Cialis / Viagra) known as a PDE-5 inhibitor. When sexually stimulated, it helps maintain a relaxed muscle state and increase the flow of blood to the penis which helps facilitate an erection.

  • How much is Spedra?

    Spedra, can vary in price from genuine UK online pharmacies, from between £2.95/ Tablet, to £7.25 / tablet, depending on strength and quantity.

  • What is the dosage of Spedra?

    Usually, when starting to take Spedra, your doctor will recommend starting on a 100mg dose. This means you will take a 100mg tablet, around 15-30 minutes before sexual activity. The maximum dose is one DOSE in a 24 hour period (up to 200mg as a single dose).

  • What is the difference between Spedra and Viagra?

    The main difference between Spedra and Viagra is that Spedra starts to work quicker than Viagra.

  • Can I take Spedra at the same time as other Erectile Dysfunction Medication?

    No. Spedra, and other ED medications such as Cialis, Levitra or Viagra, all work in the same way. This means that taking them together can result in overdose, and side effects.

  • Will Spedra always work?

    Unfortunately not. Spedra has been shown to work in around 83% of cases. Drinking before taking Spedra can also impact its effectiveness.

  • Can I drink while taking Spedra?

    Alcohol can increase the symptoms of erectile dysfunction, so it is recommended to avoid drinking. There is no chemical interaction between Spedra and alcohol, however, the risk of side effects increases and the treatment may not be as effective, or ineffective

  • When should I take Spedra?

    You should take Spedra around 15-30 minutes before sexual activity if taken on an empty stomach. If you have eaten, taking Spedra approximately 45-60 minutes before sexual activity is recommended.

  • What dose of Spedra should I start with?

    If taking Spedra for the first time, the recommended dose is 100mg, 15-30 minutes before sexual activity. The dose can then be increased or decreased according to response.

  • Is Spedra legal in the UK?

    Yes. Spedra is a legal drug in the UK which can be prescribed by a doctor.

  • Is it safe to buy Spedra online?

    As long as you check that you are purchasing from the UK registered pharmacy, regulated by the MHRa and GPHC, it should be safe for you to buy Spedra online. You should also answer any associated assessments honestly, so doctors can make the best decision as to whether you can be safely prescribed the medication.

  • Can you buy Spedra over the counter in the UK?

    No. Spedra is only available as a prescription medication in the UK.



Treatment Comparison

Active IngredientSildenafilSildenafilTadalafilTadalafilVardenafilAvanafil
Time to Take Effect30-60 mins30-60 mins15-45 mins15-45 mins30-60 mins15-30 mins
Duration of Action4-6 hours4-6 hours24-36 hours24-36 hours4-6 hours4-6 hours
Unique FeatureSame active ingredient as ViagraMost well knownSame active ingredient as CialisLongest ActingUsed for diabeticsQuickest Acting
Price Per TabletFrom £1.04From £3.44From £8.25From £5.15From £3.05

Side Effects

Side Effects of Spedra

With any medication you take, there is always a risk of side effects occurring. Some are more common than others, and often side effects may subside with the regular usage of the medicine. If the side effects do not subside, you should report them to us, or your GP.

Common Side Effects

  • Headaches
  • Flushing
  • Runny/stuffed nose
  • Upset stomach
  • Nausea
  • Red and/or warm skin
  • Dizziness
  • Diarrhoea
  • Nose bleeds
  • Muscle pain / Back Pain

The side effects listed below are more serious, and you should stop taking Spedra, and report these to your GP immediately.

  • An erection that will not go away (priapism). If you have an erection that lasts more than 4 hours, seek medical help immediately. Priapism can permanently damage your penis.
  • Sudden vision loss in one or both eyes. Sudden vision loss in one or both eyes can be a sign of a serious eye problem called non-arteritic anterior ischemic optic neuropathy (NAION). Stop taking Spedra and call your healthcare provider right away if you have sudden vision loss in one or both eyes.
  • Sudden hearing decrease or hearing loss. Some people may also have ringing in their ears (tinnitus) or dizziness. If you experience these symptoms, stop taking Spedra and contact a doctor right away.

For a full list of side effects, please read the patient information leaflet.


Info Leaflet

Before taking any medication, it is important to read the Patient Information Leaflet. You can find information leaflets for your medicines by typing them into the search bar at medicines.org, or by contacting us.

Order within for guaranteed next day delivery options


£19.99 - £94.95
Quantity 4 - 32

The above pricing is for indicative purposes only.

£20.95 - £134.95
Quantity 4 - 32

The above pricing is for indicative purposes only.

£29.95 - £184.95
Quantity 4 - 32

The above pricing is for indicative purposes only.

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Medication Simple Online Pharmacy MedExpress
Assured Pharmacy
10mg Dispersible x32 £199.95
10mg Dispersible x24 £159.95
10mg Dispersible x16 £114.50
10mg Dispersible x8 £59.95
10mg Dispersible x4 £40.95
20mg x32 £219.95
20mg x24 £169.99
20mg x16 £115.50
£169.99 £169.99
20mg x8 £60.95
£89.99 £99.99
20mg x4 £31.95
£46.99 £55.00
10mg x32 £169.95
10mg x24 £124.50
10mg x16 £89.99
£132.99 £119.99
10mg x8 £49.99
£69.99 £60.00
10mg x4 £29.65
£42.99 £43.99
5mg x32 £94.95
5mg x24 £83.95
5mg x16 £67.95
5mg x8 £45.65
£62.99 £59.99
5mg x4 £23.45
£36.99 £37.00


Medication Simple Online Pharmacy MedExpress
Assured Pharmacy
200mg x32 £184.95
£269.99 N/A
200mg x16 £99.50
£134.99 N/A
200mg x12 £76.95
200mg x8 £57.95
£69.99 N/A
200mg x4 £29.95
£36.99 N/A
100mg x32 £134.95
£199.99 N/A
100mg x16 £74.50
£99.99 N/A
100mg x12 £57.95
100mg x8 £39.50
£54.99 N/A
100mg x4 £20.95
£28.99 N/A
50mg x32 £94.95
£169.99 N/A
50mg x16 £49.99
£89.99 N/A
50mg x12 £39.95
50mg x8 £29.95
£49.99 N/A
50mg x4 £19.99
£24.99 N/A


Medication Simple Online Pharmacy MedExpress
Assured Pharmacy
100mg x64 £91.99
£139.99 £127.99
100mg x48 £69.99
100mg x32 £49.95
£89.99 £71.99
100mg x24 £39.99
£69.99 N/A
100mg x16 £25.99
£49.99 £47.99
100mg x12 £22.99
100mg x8 £16.99
£29.99 £29.99
100mg x4 £9.95
£19.99 £16.00
50mg x64 £87.95
£139.99 £127.99
50mg x48 £68.95
50mg x32 £48.95
£89.99 £71.99
50mg x24 £38.99
£69.99 N/A
50mg x16 £24.99
£49.99 £47.99
50mg x12 £21.99
50mg x8 £15.99
£29.99 £29.99
50mg x4 £9.75
£19.99 £16.00
25mg x64 £54.95
£89.99 £96.00
25mg x48 £49.95
25mg x32 £39.50
£79.99 £71.99
25mg x24 £29.95
£69.99 N/A
25mg x16 £22.50
£49.99 £47.99
25mg x12 £19.95
25mg x8 £12.95
£29.99 £29.99
25mg x4 £7.95
£15.99 £16.00


Medication Simple Online Pharmacy MedExpress
Assured Pharmacy
100mg x64 £449.95
£499.99 £539.99
100mg x32 £235.95
£249.99 £289.99
100mg x16 £121.50
£139.99 £149.99
100mg x12 £95.95
100mg x8 £63.95
£69.99 £79.99
100mg x4 £33.50
£34.99 £47.00
50mg x64 £399.95
£479.99 £519.99
50mg x32 £209.95
£235.99 £285.99
50mg x16 £112.00
£139.99 £149.99
50mg x12 £89.99
50mg x8 £58.95
£69.99 £76.99
50mg x4 £29.95
£34.99 £46.00
25mg x64 £309.95
£439.99 £419.99
25mg x32 £159.95
£219.99 £219.99
25mg x16 £81.95
£119.99 £129.99
25mg x12 £61.95
25mg x8 £43.95
£59.99 £69.90
25mg x4 £24.95
£29.99 £45.00


Medication Simple Online Pharmacy MedExpress
Assured Pharmacy
10mg (When Required Dose) x4 £8.95
£19.99 £19.98
10mg (When Required Dose) x8 £15.95
£29.99 £34.98
10mg (When Required Dose) x12 £22.95
£39.99 £49.99
10mg (When Required Dose) x16 £25.45
£49.99 £59.50
10mg (When Required Dose) x32 £43.95
£89.99 £89.50
10mg (When Required Dose) x64 £84.95
£139.99 £139.98
20mg (When Required Dose) x4 £9.75
£19.99 £19.98
20mg (When Required Dose) x8 £15.95
£29.99 £34.98
20mg (When Required Dose) x12 £23.80
N/A £49.99
20mg (When Required Dose) x16 £28.45
£49.99 £59.50
20mg (When Required Dose) x32 £53.95
£89.99 £89.50
20mg (When Required Dose) x64 £99.95
£139.99 £139.98
5mg (Daily Dose) x28 £22.85
5mg (Daily Dose) x56 £44.85
5mg (Daily Dose) x84 £66.95
2.5mg (Daily Dose) x28 £19.85
2.5mg (Daily Dose) x56 £38.50
2.5mg (Daily Dose) x84 £56.50

Viagra Connect

Medication Simple Online Pharmacy MedExpress
50mg x4 £18.48
£17.99 £19.99 £19.99
50mg x8 £31.98
£33.99 £34.99 £34.99
50mg x12 £49.98
£50.99 £51.99 £50.99
50mg x16 £63.50
£67.99 N/A N/A
50mg x32 £109.95
£139.99 N/A N/A


Medication Simple Online Pharmacy
20mg x32 £197.95
20mg x24 £150.95
20mg x16 £103.95
20mg x8 £52.95
20mg x4 £29.95
10mg x32 £133.95
10mg x24 £102.95
10mg x16 £80.95
10mg x8 £44.95
10mg x4 £25.95
5mg x32 £87.75
5mg x24 £77.75
5mg x16 £62.95
5mg x8 £36.65
5mg x4 £17.99

Vitaros Cream

Medication Simple Online Pharmacy
3mg/g x4 Sachets £61.25
3mg/g x8 Sachets £108.99
3mg/g x12 Sachets £153.99