Authored: 03/08/2022

You can request to buy Spedra tablets for erectile dysfunction online, from our UK registered online pharmacy and doctor service. After completing your online consultation and checking out, your order will be passed to our UK registered doctors for review. If approved, our pharmacy team will dispense and dispatch your medication to your chosen address.
Spedra is one of the newest and lesser-known treatments for erectile dysfunction. It contains the active ingredient Avanafil and is available in 50mg, 100mg and 200mg strengths.
It is a PDE5 inhibitor, which is the same class of medicine as the more well known ED treatments, Viagra and Cialis. While not as well known, Spedra is the fastest acting erectile dysfunction medication taking 15 to 30 minutes to work.
It works by increasing blood flow into the erectile tissue of the penis. This improves mens ability to get an erection. It does not have an impact on libido, only your ability to get and maintain an erection when sexually aroused. Generally, the amount of sexual stimulation to gain and maintain an erection is lowered.
About 60-70% of men gain a firmer and longer-lasting erection. If the treatment does not work, ask our doctors (or your own GP), whether it would be appropriate to increase the dose. Alternatively, they may recommend another treatment.
It may not work for you on your first doses. This is normal. Doctors recommend trying the treatment up to 8 times before seeking out an alternative treatment.
Dosage | Take one tablet 15-30 minutes before sex. |
Active Ingredient | Avanafil |
Available Strengths | 50mg, 100mg & 200mg tablets |
How it works | Increases blood flow into the penis, allowing erections to occur more easily. |
Side effects | Can include nasal congestion, headaches, facial flushing, slight vertigo, a pounding heartbeat, and blurred vision. |
There are a number of possible alternatives to treat ED.
Alternative treatment options fall into three main groups
All of our medication and condition content is written by UK qualified pharmacists and doctors.
Authored: 03/08/2022
Reviewed: 26/02/2025
Spedra is a medicine used in the treatment of erectile dysfunction in men.
Spedra is a PDE‑5 inhibitor. When sexually stimulated, it helps maintain a relaxed muscle state and increases blood flow to the penis, thereby facilitating an erection.
The price of Spedra from genuine UK online pharmacies can vary from approximately £2.97 per tablet to £7.25 per tablet, depending on the strength and quantity.
The main difference is that Spedra starts to work quicker than Viagra.
Take Spedra 15–30 minutes before sexual activity if you are on an empty stomach. If you have eaten, wait approximately 45–60 minutes before engaging in sexual activity.
Spedra has been shown to work in a majority of cases, though individual responses can vary. If it doesn’t work as expected, consult your doctor for alternative treatments.
No. Spedra, like other ED medications, works in the same way. Taking it alongside other ED drugs can result in an overdose and increase the risk of side effects.
Spedra, as a PDE‑5 inhibitor, may interact with nitrates and certain other medications. It is important to disclose all your current medications to your doctor before starting Spedra.
Yes. Spedra is a legal medicine in the UK and can be prescribed by a doctor.
Yes, as long as you purchase from a UK‑registered pharmacy regulated by the MHRA and GPHC, and complete the necessary assessments accurately, it is safe to buy Spedra online.
No. Spedra is only available as a prescription medication in the UK.
Sildenafil | Viagra | Tadalafil | Cialis | Vardenafil | Levitra | Spedra | |
Active Ingredient | Sildenafil | Sildenafil | Tadalafil | Tadalafil | Vardenafil | Vardenafil | Avanafil |
Time to Take Effect | 30-60 mins | 30-60 mins | 15-45 mins | 15-45 mins | 30-60 mins | 30-60 mins | 15-30 mins |
Duration of Action | 4-6 hours | 4-6 hours | 24-36 hours | 24-36 hours | 4-6 hours | 4-6 hours | 4-6 hours |
Unique Feature | Same active ingredient as Viagra | Most well known | Same active ingredient as Cialis | Longest Acting | Used for diabetics | Used for diabetics | Quickest Acting |
Price Per Tablet | From 78p | From £4.84 | From 67p | From £2.26 | From £2.74 | From £2.97 | From £2.97 |
With any medication you take, there is always a risk of side effects occurring. Some are more common than others, and often side effects may subside with the regular usage of the medicine. If the side effects do not subside, you should report them to us, or your GP. Some of the more common side effects of Spedra include
The side effects listed below are more serious, and you should stop taking Spedra, and report these to your GP immediately.
For a full list of side effects, please read the patient information leaflet.
Before taking any medication, it is important to read the Patient Information Leaflet.
The recommended starting dose is Spedra 100mg. Your doctor may decide to start you on a different strength based on factors such as age and weight. It is recommended to use the lowest effective dose as this often produces fewer side effects.
One tablet should be taken 15-30 minutes before sexual activity. If 100mg is too strong, you may break the tablet into a smaller dose.
Avoid grapefruit juice for at least 24 hours before taking this treatment. Grapefruit juice can increase exposure to the medicine resulting in increased side effects.
If the 100mg does not achieve the desired result, you may wish to try the same dose 2-3 more times, before increasing the dosage to Spedra 200mg. If a 200mg dose is ineffective speak to your doctor about alternative treatments.
Different patients will find different medicines more effective. This does not always mean one medicine is better than another, just that your body responds slightly differently to one medicine over another.
Spedra cannot be prescribed by our doctor if you are taking nicorandil or nitrate-based medication, such as GTN spray or isosorbide mononitrate tablets for angina.
If you are taking alpha-blocking medicines, such as tamsulosin or trazodone, you are advised to leave at least six hours between taking your alpha-blocker and Spedra.
For a full list of people who should avoid using this medicine, visit the patient information leaflet.