Authored: 03/08/2022
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Spedra
Overview
- Fastest acting ED medication
- Works within 15-30 minutes
- Can work for up to 6 hours
- Contains Avanafil
Overview
Order Spedra (Avanafil) Online
You can request to buy Spedra tablets for erectile dysfunction online, from our UK registered online pharmacy and doctor service. After completing your online consultation and checking out, your order will be passed to our UK registered doctors for review. If approved, our pharmacy team will dispense and dispatch your medication to your chosen address.
What Is Spedra?
Spedra is one of the newest and lesser-known treatments for erectile dysfunction. It contains the active ingredient Avanafil and is available in 50mg, 100mg and 200mg strengths.
It is a PDE5 inhibitor, which is the same class of medicine as the more well known ED treatments, Viagra and Cialis. While not as well known, Spedra is the fastest acting erectile dysfunction medication taking 15 to 30 minutes to work.
How Does Spedra Work?
It works by increasing blood flow into the erectile tissue of the penis. This improves mens ability to get an erection. It does not have an impact on libido, only your ability to get and maintain an erection when sexually aroused. Generally, the amount of sexual stimulation to gain and maintain an erection is lowered.
Is Spedra Effective?
About 60-70% of men gain a firmer and longer-lasting erection. If the treatment does not work, ask our doctors (or your own GP), whether it would be appropriate to increase the dose. Alternatively, they may recommend another treatment.
It may not work for you on your first doses. This is normal. Doctors recommend trying the treatment up to 8 times before seeking out an alternative treatment.
Spedra Summary
Dosage | Take one tablet 15-30 minutes before sex. |
Active Ingredient | Avanafil |
Available Strengths | 50mg, 100mg & 200mg tablets |
How it works | Increases blood flow into the penis, allowing erections to occur more easily. |
Side effects | Can include nasal congestion, headaches, facial flushing, slight vertigo, a pounding heartbeat, and blurred vision. |
Alternative to Spedra
There are a number of possible alternatives to treat ED.
Alternative treatment options fall into three main groups
- Other drug treatments
- Physical Devices, such as penis pumps
- Counselling. It's possible that your ED is psychological in nature. Counselling and psychotherapy can help if this is one of the underlying causes of your condition.
Written by Qualified Experts
All of our medication and condition content is written by UK qualified pharmacists and doctors.
Reviewed: 26/02/2025
FAQ
General Information
What is Spedra?
Spedra is a medicine used in the treatment of erectile dysfunction in men.
How does Spedra work?
Spedra is a PDE‑5 inhibitor. When sexually stimulated, it helps maintain a relaxed muscle state and increases blood flow to the penis, thereby facilitating an erection.
How much is Spedra?
The price of Spedra from genuine UK online pharmacies can vary from approximately £2.97 per tablet to £7.25 per tablet, depending on the strength and quantity.
What is the difference between Spedra and Viagra?
The main difference is that Spedra starts to work quicker than Viagra.
Usage & Dosage
When should I take Spedra?
Take Spedra 15–30 minutes before sexual activity if you are on an empty stomach. If you have eaten, wait approximately 45–60 minutes before engaging in sexual activity.
Effectiveness & Results
Will Spedra always work?
Spedra has been shown to work in a majority of cases, though individual responses can vary. If it doesn’t work as expected, consult your doctor for alternative treatments.
Side Effects & Safety
Can I take Spedra with other ED medications?
No. Spedra, like other ED medications, works in the same way. Taking it alongside other ED drugs can result in an overdose and increase the risk of side effects.
Interactions
Are there any specific drug interactions with Spedra?
Spedra, as a PDE‑5 inhibitor, may interact with nitrates and certain other medications. It is important to disclose all your current medications to your doctor before starting Spedra.
Access & Cost
Is Spedra legal in the UK?
Yes. Spedra is a legal medicine in the UK and can be prescribed by a doctor.
Is it safe to buy Spedra online?
Yes, as long as you purchase from a UK‑registered pharmacy regulated by the MHRA and GPHC, and complete the necessary assessments accurately, it is safe to buy Spedra online.
Can you buy Spedra over the counter in the UK?
No. Spedra is only available as a prescription medication in the UK.
Compare
Treatment Comparison
| Sildenafil | Viagra | Tadalafil | Cialis | Vardenafil | Levitra | Spedra | |
| Active Ingredient | Sildenafil | Sildenafil | Tadalafil | Tadalafil | Vardenafil | Vardenafil | Avanafil |
| Time to Take Effect | 30-60 mins | 30-60 mins | 15-45 mins | 15-45 mins | 30-60 mins | 30-60 mins | 15-30 mins |
| Duration of Action | 4-6 hours | 4-6 hours | 24-36 hours | 24-36 hours | 4-6 hours | 4-6 hours | 4-6 hours |
| Unique Feature | Same active ingredient as Viagra | Most well known | Same active ingredient as Cialis | Longest Acting | Used for diabetics | Used for diabetics | Quickest Acting |
| Price Per Tablet | From 78p | From £4.84 | From 67p | From £2.26 | From £2.74 | From £2.97 | From £2.97 |
Side Effects
Spedra Side Effects
With any medication you take, there is always a risk of side effects occurring. Some are more common than others, and often side effects may subside with the regular usage of the medicine. If the side effects do not subside, you should report them to us, or your GP. Some of the more common side effects of Spedra include
- Headaches
- Flushing
- Runny/stuffed nose
- Upset stomach
- Nausea
- Red and/or warm skin
- Dizziness
- Diarrhoea
- Nose bleeds
- Muscle pain / Back Pain
The side effects listed below are more serious, and you should stop taking Spedra, and report these to your GP immediately.
- An erection that will not go away (priapism). If you have an erection that lasts more than 4 hours, seek medical help immediately. Priapism can permanently damage your penis.
- Sudden loss of vision in one or both eyes. Sudden vision loss in one or both eyes can be a sign of a serious eye problem called non-arteritic anterior ischemic optic neuropathy (NAION). Stop taking Spedra and call your healthcare provider right away if you have sudden vision loss in one or both eyes.
- Sudden hearing decrease or hearing loss. Some people may also have ringing in their ears (tinnitus) or dizziness. If you experience these symptoms, stop taking Spedra and contact a doctor right away.
For a full list of side effects, please read the patient information leaflet.
Reviews
Info Leaflet
Before taking any medication, it is important to read the Patient Information Leaflet.
Directions
Spedra Dosage
The recommended starting dose is Spedra 100mg. Your doctor may decide to start you on a different strength based on factors such as age and weight. It is recommended to use the lowest effective dose as this often produces fewer side effects.
One tablet should be taken 15-30 minutes before sexual activity. If 100mg is too strong, you may break the tablet into a smaller dose.
Avoid grapefruit juice for at least 24 hours before taking this treatment. Grapefruit juice can increase exposure to the medicine resulting in increased side effects.
If the 100mg does not achieve the desired result, you may wish to try the same dose 2-3 more times, before increasing the dosage to Spedra 200mg. If a 200mg dose is ineffective speak to your doctor about alternative treatments.
Different patients will find different medicines more effective. This does not always mean one medicine is better than another, just that your body responds slightly differently to one medicine over another.
Warnings
Do not take Spedra:
- If you have uncontrolled low or high blood pressure.
- If you have a serious heart condition
- If you experience chest pain from angina and take nitrate medicines
- If you have any allergies to the ingredients listed
- If you have had a stroke or heart attack in the last 6 months
Spedra cannot be prescribed by our doctor if you are taking nicorandil or nitrate-based medication, such as GTN spray or isosorbide mononitrate tablets for angina.
If you are taking alpha-blocking medicines, such as tamsulosin or trazodone, you are advised to leave at least six hours between taking your alpha-blocker and Spedra.
For a full list of people who should avoid using this medicine, visit the patient information leaflet.
