Xenical Capsules
  • Xenical Capsules

Xenical Capsules

Medication features

  • Cheaper Generic >>> Orlistat
  • Reduces the amount of fat the body absorbs
  • Should be used as part of an exercise / diet programme


Order Xenical Weight Loss Tablets Online

You can request to order Xenical UK weight loss medication online, from our UK registered online pharmacy and doctor service. After completing your assessment and checking out, your order will be passed to our UK registered doctors for review. If approved, our pharmacy team will dispense and dispatch your medication to your chosen address via Royal Mail.

What is Xenical?

Xenical is a weight loss pill, which contains the active ingredient, Orlistat. It is used to aid weight loss in men and women who have a high BMI, and may need assistance in losing weight. Combined with a balanced diet and regular exercise, Xenical can increase your chances of losing extra weight. 

How does it work?

Xenical works by preventing around a third of the fat from the food you eat from being digested. The undigested fat is not absorbed and is passed out with your faeces.  

This helps you avoid gaining weight but it does not necessarily cause you to lose weight. Therefore, it’s still important to stick to your recommended diet and exercise plan. See our recent blog post on how to get the best results from orlistat for more information.

Xenical is usually recommended if you have made a significant effort to lose weight through diet, exercise or changing your lifestyle. Even then, it is only prescribed if you have:

Treatment must be combined with a low-fat diet and other weight-loss strategies, such as doing more exercise. It is not recommended for pregnant or breastfeeding women.

How to take Xenical

It should be taken exactly as your doctor has told you to. Typically, the dose is one tablet taken with each of your three meals a day. You should not take more than 3 tablets a day. A dose can be taken either before, during, or up to one hour after a meal.

Xenical works by reducing the amount of fat absorbed by your body. This means that if you eat a meal that contains no fat, there is no need to take a dose. Usually, your doctor will see how you progress with Xenical over 12 weeks. If you have not lost a minimum of 5% of your body weight, treatment should be stopped.

Who can take Xenical?

Xenical can be used in people who are medically obese.  This is usually defined as people who have a BMI of over 30. We can also prescribe this medication for people who have a BMI of over 28 if they have certain other health conditions, such as diabetes or heart disease. 

We are unable to prescribe this medication if you are pregnant or breastfeeding.

Alternatives to Xenical

There are a number of other options available to someone looking to lose weight. These may be exclusively diet and exercise based, or include other over the counter or prescription medications.

Saxenda, is a relatively new weight loss aid, which works a little differently from Xenical. Instead of reducing fat absorption, it instead makes you feel more full and less hungry. 


How Does Xenical Work?

It works by binding to the enzymes in the body to prevent the absorption of fat. On average, Xenical will work on around a quarter to one-third of the fat you eat. Instead of this fat being absorbed, it passes through your gut. For people with high-fat diets, this can result in oily stools.

What to eat when taking Xenical?

Xenical treatment is recommended alongside a low-calorie intake diet. One of our pharmacists has written a recent blog post that discusses an ‘orlistat diet’ and how to optimise Xenical (orlistat) treatment. It is important to try to spread your daily intake of fat across all three meals of the day.

Who can use Xenical?

Xenical 120mg capsules are indicated in people with a BMI over 30. It can also be prescribed to people who have a BMI over 28, with another weight-related condition, such as diabetes or high blood pressure.

What is the difference between Xenical and Orlistat?

Xenical is the branded version of the drug, orlistat. Medically, they are exactly the same drug and contain exactly the same strength (120mg of orlistat).

What is the difference between Orlistat / Xenical and Alli?

Alli is an over the counter version of Xenical, which is half the strength of the prescribed version. Alli contains 60mg of orlistat, compared to 120mg in Xenical and generic prescription Orlistat.

What is the dosage and duration of treatment of Xenical?

One capsule is taken with each main meal (to a maximum of three capsules daily). You can take the capsule before, during or up to one hour after each meal.

If you miss a meal or the meal does not contain any fat, you may not need to take the orlistat capsule; check the patient information leaflet that comes with your medication.

Treatment with Orlistat (Xenical) should only continue beyond three months if you have lost 5% of your body weight. It usually starts to affect how you digest fat within one to two days. If orlistat has not worked after three months, it is unlikely to be an effective treatment for you.

If you have type 2 diabetes, it can take longer to lose weight using Orlistat, so your target weight loss after three months may, therefore, be slightly lower.

If Orlistat is successful after three months, your prescription may be continued for up to a year. After that, your GP will review your condition and decide whether you should continue with Orlistat.

How effective is Xenical?

It helps to reduce fat absorption by 25-33%. In clinical trials, patients on Xenical are twice as likely to lose over 10% of their body weight over the course of a year, in comparison to someone using diet alone. It should be noted, when taking Xenical, diet and exercise are still key in achieving the best results. 

Can you buy Xenical over the counter?

Xenical is not available over the counter and you need a prescription for it. At Simple Online Pharmacy, our online doctors are able to prescribe Xenical online for our pharmacy to deliver. You will need to fill in an online assessment for our doctors to review. This helps them decide if it is suitable for you.

Although Xenical 120mg is not available over the counter, the lower strength version is. This is called Alli 60mg and you can speak to a pharmacist to purchase it over the counter.

Content Reviewed: 12/01/2021


Treatment Comparison

IngredientOrlistat 60mgOrlistat 120mgOrlistat 120mg
MechanismReduces fat absorptionReduces fat absorptionReduces fat absorption
DoseOne three times daily with mealsOne three times daily with mealsOne three times daily with meals

Side Effects

What are the side effects Of Xenical?

Every medication has the possibility of causing side effects, some are more common than others. Common side effects of Xenical include:

  • Fatty or oily stools
  • Needing the toilet urgently
  • Passing stools frequently
  • Oily discharge from your rectum (you may have oily spots on your underwear)
  • Flatulence (wind)
  • Stomach pain or discomfort
  • Headaches 

The majority of these side effects are mild and generally happen at the start of treatment. Usually, these side effects subside after continuing treatment with a healthy diet. Some of these side effects are more common if a dose is taken with a very high-fat meal.
Further information on side effects can be found in the patient information leaflet. If you experience any unusual or bothersome side effects, speak to your pharmacist or doctor for advice.


Info Leaflet

Before taking any medication, it is important to read the Patient Information Leaflet.

Xenical Information Leaflet



Marketing Authorisation Holder:

CHEPLAPHARM Arzneimittel GmbH

Ziegelhof 24

17489 Greifswald



Other conditions and Xenical

It is not suitable for everyone. People with the following should not take Xenical:

  • An allergy to orlistat or any of the ingredients in Xenical
  • The liver disorder cholestasis
  • Chronic malabsorption syndrome 

See the patient information leaflet for further details.

Interactions with other medicines

Xenical can have an effect on some medicines such as warfarin and levothyroxine. See the patient information leaflet or speak to your doctor or pharmacist for advice. The dose of some medicines may need to be changed if you lose weight.

Xenical can cause severe diarrhoea as a side effect and if this occurs, it can reduce the effectiveness of the contraceptive pill. If this is the case, you should use additional contraceptive methods (e.g. condoms).

Xenical can reduce the amount of certain vitamins your body absorbs. Due to this, your doctor may recommend you take a multivitamin supplement.

Order within for guaranteed next day delivery options


Prices From £44.50
As low as £0.52 / Capsule

Compare Prices
The variation selected is currently out of stock.
Item added to bag. Click here to view bag.
Please select a size from above to proceed.
There are NHS prescriptions in your basket. Please complete the order first or remove NHS prescriptions from the basket.


Medication Simple Online Pharmacy MedExpress
Assured Pharmacy
120mg x252 £98.95
£149.99 £120.00
120mg x168 £67.95
£109.99 £90.00
120mg x84 £34.00
£68.99 £53.00
120mg x42 £17.50

Xenical Capsules

Medication Simple Online Pharmacy MedExpress
252 £130.50
168 £87.99
84 £44.50


Medication Simple Online Pharmacy
Saxenda Pens Only(No Needles) x1 £51.00
Saxenda Pens Only(No Needles) x2 £100.00
Saxenda Pens Only(No Needles) x3 £150.00
Saxenda Pens Only(No Needles) x4 £200.00
Saxenda Pens Only(No Needles) x5 £240.00
Pens + Sharps Bin x1 - + Sharps Bin £54.00
Pens + Sharps Bin x2 - + Sharps Bin £103.00
Pens + Sharps Bin x3 - + Sharps Bin £153.00
Pens + Sharps Bin x4 - + Sharps Bin £203.00
Pens + Sharps Bin x5 - + Sharps Bin £243.00
Pens + Sharps Bin + Replacement Needle Heads x1 - + Sharps Bin + Needles £57.00
Pens + Sharps Bin + Replacement Needle Heads x2 - + Sharps Bin + Needles £106.00
Pens + Sharps Bin + Replacement Needle Heads x3 - + Sharps Bin + Needles £155.00
Pens + Sharps Bin + Replacement Needle Heads x4 - + Sharps Bin + Needles £205.00
Pens + Sharps Bin + Replacement Needle Heads x5 - + Sharps Bin + Needles £245.00
Pens + Replacement Needle Heads x1 - + Needles £55.00
Pens + Replacement Needle Heads x2 - + Needles £104.00
Pens + Replacement Needle Heads x3 - + Needles £154.00
Pens + Replacement Needle Heads x4 - + Needles £204.00
Pens + Replacement Needle Heads x5 - + Needles £244.00
Saxenda Pens Only(No Needles) x10 £475.00
Pens + Sharps Bin x10 - + Sharps Bin £478.00
Pens + Sharps Bin + Replacement Needle Heads x10 - + Sharps Bin + Needles £480.00
Pens + Replacement Needle Heads x10 - + Needles £479.00