Prochlorperazine 5mg
  • Prochlorperazine 5mg


Medication features

  • Prescription anti-sickness medicine
  • Works in around 30 to 60 minutes
  • Short term use only


Order Prochlorperazine Online UK

You can request to order Prochlorperazine 5mg tablets online from our UK registered online doctor and pharmacy service. Once you have completed an online doctor consultation, our UK trained and registered GPs will review your assessment. 

If approved, a prescription is then sent to our UK pharmacy team who will dispense and dispatch the medicine to your chosen address. Please note, this service is only available to people who have been prescribed this previously from their GP.

What is Prochlorperazine?

Prochlorperazine is an anti-sickness medicine. It can be used to stop you being sick or feeling sick (nausea). It can help with nausea and vomiting caused by different conditions such as migraines, Meniere’s disease, travel sickness, and morning sickness.

Prochlorperazine can also be taken for vertigo. The active ingredient is prochlorperazine maleate. Prochlorperazine tablets are only available on prescription in the UK.

However, you can buy Prochlorperazine buccal tablets over the counter at your local pharmacy. These are placed between the upper lip and the gum until they dissolve. They can be sold to treat nausea and vomiting associated with migraines. You can buy the brand Buccastem M online from our online pharmacy. 

How does it work?

Prochlorperazine is a type of medicine called a phenothiazine. It’s thought to improve nausea because it blocks the action of a chemical, dopamine, in the brain. This helps prevent messages being sent to the part of the brain thought to be responsible for nausea and vomiting.

Prochlorperazine can help prevent nausea and vomiting and can also improve symptoms if you’re currently experiencing nausea and vomiting.

Prochlorperazine alternatives

Various medicines are available to help prevent or treat nausea and vomiting. Medicines like Hyoscine (Kwells), cinnarizine, and promethazine are used to aid travel sickness. For nausea associated with migraines, a medicine called buclizine can be an effective treatment. This is one of the active ingredients in Migraleve Pink tablets.

Other medicines can be prescribed to treat nausea and vomiting such as metoclopramide, domperidone, cyclizine and ondansetron. They are used to treat nausea and vomiting caused by many conditions such as morning sickness, vertigo and nausea after an operation.

Prochlorperazine summary

Used to treat

General nausea and vomiting, vertigo, Meniere's disease

How it works

Blocks nausea messages to the brain



Side effects

Can include drowsiness, dizziness, dry mouth, and constipation


What is prochlorperazine 5mg used for?

Prochlorperazine, in the UK, can be used for various conditions that cause nausea and vomiting such as migraines, vertigo, and Meniere’s disease. It can also be used as a short term treatment for anxiety and is used in the management of certain mental illnesses like mania. 

What does prochlorperazine do for vertigo?

It’s useful for vertigo because it can help to relieve the severe nausea and vomiting associated with vertigo.

How many prochlorperazine 5mg tablets can I take?

You should take this medicine exactly as your doctor has told you to. They will tell you the maximum amount of tablets to take per day.

Can you buy prochlorperazine over the counter in the UK?

You cannot buy prochlorperazine 5mg tablets over the counter in the UK. This medicine is only available on prescription. However, you can buy prochlorperazine buccal tablets over the counter at your local pharmacy.

These are placed between the upper lip and the gum until they dissolve. They can be sold to treat nausea and vomiting associated with migraines.

How long does prochlorperazine take to work?

The tablets should start to work within an hour of taking them. You should notice your nausea or vomiting improve after this time. For other conditions, like Meniere’s disease, it may take several days to have a full effect.

Side Effects

Prochlorperazine Side Effects

As with any medicine, taking prochlorperazine may cause side effects for some people. Some common side effects include dry mouth, constipation, dizziness, blurred vision and drowsiness. 

There is also a possibility of rare but serious side effects. This includes a severe allergic reaction that can cause swelling of the face, lips and tongue and lead to breathing problems. Other serious problems include blood problems like leukopenia and a side effect called neuroleptic malignant syndrome. You can find more information on these side effects and others in section 4 of the patient information leaflet.


Info Leaflet

Before taking any medication, it is important to read the Patient Information Leaflet.


Prochlorperazine Dosage

How to take Prochlorperazine

The dose of prochlorperazine is different depending on the condition being treated. For nausea and vomiting, the usual dose is one or two 5mg tablets two or three times a day. Your doctor will discuss the correct dose for you and you should take it exactly as your doctor tells you. The usual dose for vertigo is one 5mg tablet three times a day.

See the patient information leaflet for further information on how to take the tablets.


This medicine is not suitable for everyone to take. It should not be taken by anyone who has had an allergic reaction in the past to prochlorperazine or any of the ingredients in the tablets. It may also not be suitable for people with heart problems, kidney or liver problems, epilepsy, glaucoma and adrenal gland tumours.

This is not a complete list of warnings for this medicine. See the patient information leaflet or talk to your doctor or pharmacist for more information.

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