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Real patient results

How Much Weight Do People Lose on Mounjaro?

Real-world results from 213,263 UK patients treated through Simple Online Pharmacy.

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Top 25% of patients

23 kg lost by 12 months

What these results show
Top 25% Mounjaro weight loss over 12 months 12 kilograms at 3 months, 17 kilograms at 6 months, and 23 kilograms at 12 months. 12 kg 3 months 17 kg 6 months 23 kg 12 months
Top 25% of patients: 12 kg at 3 months, 17 kg at 6 months, 23 kg at 12 months.

Observed outcomes from 213,263 UK patients treated through Simple Online Pharmacy. Not a personal prediction. Individual results may vary.

Mounjaro weight loss outcomes

People respond to Mounjaro differently. This section shows observed outcomes across Simple Online Pharmacy patient groups at 3, 6, and 12 months.

At 3 months

Mounjaro weight loss distribution at 3 months
Cohort Avg loss (kg) Avg loss (%)
Top 10% of patients 16 kg 15.4%
Top 25% of patients 12 kg 12.0%
Typical patient 8 kg 8.6%

At 6 months

Mounjaro weight loss distribution at 6 months
Cohort Avg loss (kg) Avg loss (%)
Top 10% of patients 22 kg 21.6%
Top 25% of patients 17 kg 17.4%
Typical patient 12 kg 12.8%

At 12 months

Mounjaro weight loss distribution at 12 months
Cohort Avg loss (kg) Avg loss (%)
Top 10% of patients 30 kg 28.2%
Top 25% of patients 23 kg 22.5%
Typical patient 16 kg 16.4%

Mounjaro weight loss by age at 12 months

Mounjaro weight loss by age at 12 months
Age band Average loss (kg) Average loss (%)
18-24 21.0 kg 19.0%
25-34 17.6 kg 16.6%
35-44 16.9 kg 16.5%
45-54 17.0 kg 16.8%
55-64 16.8 kg 16.8%
65+ 17.1 kg 17.5%

The data presented is based on anonymised real-world outcomes from 213,263 patients treated through the Simple Online Pharmacy programme. Patients lost an average of 7 kg (around 7% body weight) over an average treatment duration of 4.6 months.

The analysis includes patients who started treatment, including non-completers, to provide a broad view of observed outcomes across the programme.

Typical patient refers to the midpoint of observed outcomes.

These findings are observational and intended to show overall patterns across large patient groups, not personal predictions or medical advice. Individual results may vary.

What these Mounjaro results show

Our real-world data shows that weight loss builds over time, but results vary considerably between patients. The typical patient in our 12-month data lost 16kg (16.4% of body weight), while one in four lost 23kg (22.5%) or more.

Medication is only part of a weight-loss journey. Individual outcomes can be influenced by factors including treatment duration, dose, starting weight, lifestyle and adherence.

Explore Mounjaro
Aamina Rafiq, Superintendent Pharmacist at Simple Online Pharmacy

Medically reviewed by

Aamina Rafiq

Superintendent Pharmacist MPharm GPhC: 2216332

This page has been reviewed by our clinical team to ensure it is clear, accurate, and up to date.

Last updated: 12 May 2026