Elleste Duo Conti
  • Elleste Duo Conti

Elleste Duet Conti

Medication features

  • Medication contains estradiol hemihydrate & norethisterone acetate
  • Helps to increase oestrogen levels
  • Helps with the growth of the  womb lining


Order Elleste Duet Conti Tablets Online

You can order Elleste Duet Conti tablets online from our UK registered online pharmacy and doctor service. You will need to complete an online assessment which will be passed onto our UK registered doctors to review. If approved by our doctors, our pharmacists will dispense and dispatch your order to your chosen address.

What is Elleste Duet Conti?

Elleste Duet Conti is a Hormone Replacement Therapy (HRT) medication used to relieve the symptoms of menopause. It can also be used to prevent osteoporosis in postmenopausal women who may be at risk of the disease. 

It contains two types of hormones. One hormone is an oestrogen (estradiol hemihydrate) and the other is a progestogen (norethisterone acetate). Elleste Duet Conti tablets contain 2mg of oestradiol and 1mg of norethisterone.

Elleste Duet Conti is called a continuous combined HRT because each tablet contains both hormones. Continuous combined HRT is recommended for women who are postmenopausal (women who have not had a period for 1 year). Other forms of HRT like cyclical HRT are recommended for women who still have menstrual periods.

How does it work?

During the menopause, the estrogen levels in the body decrease and can cause symptoms such as hot flashes, vaginal dryness, night sweats, reduced libido, and mood swings. Elleste Duet Conti contains a hormone called estradiol, which replaces the lost oestrogen in the body. This improves the symptoms associated with menopause by increasing oestrogen levels.

A rise in oestrogen levels can increase the risk of womb cancer by causing overgrowth of the endometrium. To offset this risk, Elleste Duet also contains another ingredient called norethisterone, a type of progestogen. The addition of a progestogen greatly reduces the risk of womb cancer caused by oestrogen.

Women who have had a hysterectomy are able to take oestrogen without the need for a progestogen.


Elleste Duet Conti is taken as one tablet daily at the same time every day. When you finish a strip of tablets, start another strip the next day. 

If you are more than 12 hours late taking a tablet, dispose of that tablet and take the next one at the normal time.


Other forms of HRT include:

  • Tablets
  • Gels
  • Vaginal rings
  • Skin patches
  • Vaginal pessaries
  • Vaginal creams

Our doctors are able to prescribe a number of HRT products on our website:

  • Estradot patches
  • Elleste Solo
  • Vagifem
  • Evorel Conti patches
  • Evorel Sequi patches
  • Kliovance
  • Estring
  • Elleste Duet (1mg/2mg)
  • Livial
  • Premarin
  • Premique
  • Trisequens
  • Provera

Various HRT products have suffered from product shortages in the past two years. The products can differ slightly, making it hard to find a direct alternative when one becomes unavailable to stock. 

The closest alternatives for Elleste Duet Conti are Kliofem and Indivina.


Is Elleste Duet available?

Elleste Duet is available in three strengths, 1mg, 2mg and Elleste Duet Conti.

Is Elleste Duet discontinued?

There has been a low supply of Elleste Duet stock in recent months due to manufacturing issues. However, we have Elleste Duet 1mg, Elleste Duet 2mg and Elleste Duet Conti tablets in stock.

Does Elleste Duet cause weight gain?

Weight increase is listed as a common side effect. Some women experience weight gain during the menopause regardless of whether they take HRT or not. 

What is Elleste Duet Conti used for?

Elleste Duet Conti tablets are hormone replacement therapy (HRT) tablets used to relieve menopause symptoms in menopausal women. It can also be used to prevent osteoporosis in postmenopausal women who may be at risk of the disease. 

It contains oestrogen and progestogen hormones.

How long does it take for Elleste Duet to work?

Women may start to see the benefits of HRT within a few weeks but it can take up to three months to feel the full effects.

Can I order Elleste Duet Conti online?

Yes, you can order Elleste Duet Conti online via our UK registered online pharmacy and doctor service. After having an online consultation, our doctors can assess your suitability for treatment and issue a prescription if necessary.

Side Effects

There is always a risk of side effects when taking any medicine. 

Common side effects of Elleste Duet Conti include:

  • Breast tenderness or pain
  • Diarrhoea
  • Headache
  • Libido changes
  • Stomach cramps
  • Nausea
  • Problems with your menstrual cycle
  • Mood changes

These side effects of HRT may improve over time.

The patient information leaflet contains a comprehensive list of possible side effects.

Before starting the therapy women should be aware of the potential risks of HRT. With your doctor, you should discuss whether the benefits would outweigh the risks. Women taking HRT report the following diseases more often than women who do not take HRT:

  • Endometrial cancer (the progestogen in Elleste Duet mitigates this risk)
  • Ovarian cancer
  • Heart disease
  • Blood clots (venous thromboembolism)
  • Stroke
  • Breast cancer

The increased risk of breast cancer means that, out of 1000 women using HRT, 4-6 extra women in a 5 year period will be diagnosed with breast cancer compared to non-users of HRT.

The risk of blood clots in HRT users is up to 3x higher than in non-users. The risk is highest during the first year of treatment.

The risks of taking HRT may be different in women who have early menopause. If this is the case for you, you should discuss these risks with your doctor.

Women taking HRT should be regularly checked by their doctor to monitor treatment and side effects.

The NHS website contains information on the symptoms of blood clots, breast cancer, endometrial cancer and stroke as well as information on the risks of HRT.


Info Leaflet

Before taking any medication, it is important to read the Patient Information Leaflet. You can find information leaflets for your medicines by typing them into the search bar at medicines.org, or by contacting us



Other conditions and Elleste Duet Conti

When filling out our online form, make sure to mention any medical conditions that you have.

Elleste Duet Conti should not be used in a number of conditions. If you develop any of these conditions during treatment you should stop taking HRT. Examples of these are:

  • If you currently have breast cancer or have had it in the past
  • Endometrial hyperplasia (thickening of the womb lining)
  • If you currently have cancer which is sensitive to oestrogens, such as endometrial cancer, or have had it in the past
  • If you have a blood clotting disorder
  • Recent stroke or heart attack
  • Undiagnosed vaginal bleeding
  • If you currently have a blood clot or have had blood clots in the past
  • If you currently have liver disease or have had it in the past

Interactions with other medicines

When filling out our online form, make sure to list any medicines you currently take. Elleste Duet Conti should be used in caution with a number of medicines. These include:

  • Medicines for tuberculosis
  • Medicines for epilepsy such as carbamazepine
  • The herbal medicine St John’s Wort
  • Medicines for HIV infection

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