Difflam Spray for sore throats
  • Difflam Spray for sore throats

Difflam Spray

Save 14% Now £6.00 Was £6.99

Medication features

  • Treats painful sore mouth & throat conditions
  • Collapsable nozzle for easy application
  • Also available as an oral rinse 


Buy Difflam Spray Online UK

You can buy Difflam throat spray online from our UK registered online pharmacy. After reading any relevant medical information you can place an order. Our pharmacy team will then review, dispense and dispatch your medication to your chosen address.

About Difflam Spray

Difflam Throat spray aims to relieve the symptoms of a sore throat. The active ingredient benzydamine hydrochloride acts to provide long-acting local pain relief and reduce inflammation in the throat and mouth.

  • Difflam Spray is used in the treatment of painful mouth and throat condition such as teething, mouth ulcers and sore throats.
  • Difflam Spray can be used to ease pain and reduce inflammation in viral and bacterial throat infections as well as sore throats associated with the common cold.
  • Difflam Spray comes with a collapsable nozzle for easy application to the throat and mouth

It can be used to treat a variety of painful mouth and throat conditions such as:

  • Mouth Ulcers
  • Sore throat
  • Sore tongue or gums
  • Pain associated with the use of dentures
  • Pain after dental work
  • Teething

How Does Difflam Work?

The active ingredient in Difflam spray is Benzydamine.  This works to reduce inflammation and targets pain in the throat and mouth area.

Benzydamine is a treatment known as NSAID (non steroid anti-inflammatory drug).  NSAID works to block the natural response from the body when faced with pain and inflammation.   This can result in almost instant pain relief with a temporary numbing effect in the mouth and areas it has come into contact with.

Avoid eating or drinking food or drinks that are very hot while using this product.  With the numbing effect seen in this medication it can increase the risk of burning yourself and can alter the impact you would normally feel when eating heated food and drink.

What is Difflam Spray for?

Difflam spray is intended to help soothe and give relief when suffering from mouth ulcers, sore throats, gum pain, and post dental surgery inflammation.  Difflam can also be used to help in the treatment of inflammation after tonsil removal and general sore throats.

Using Difflam Spray

Difflam Spray comes with a collapsable nozzle for easy, direct administration to the mouth and throat.

To use the spray you should pull the nozzle out to a 90-degree angle until horizontal.
You should hold the spray upright at all times.

Before you start using it, the spray needs to be ‘primed’ - this involves pressing down on the green spray plunger until a fine spray appears. The spray should be directed away from you from whilst priming. Priming the spray only needs to be done once, on first use.

After priming, your spray is ready to use. Direct the spray to the sore part of your mouth or throat. Pressing down on the green plunger again will release one spray or ‘puff’.

After using the spray, the nozzle should be wiped clean with a tissue and collapsed. This prevents any build up and ensures your spray continues to work effectively.


How many puffs to use?

Difflam spray can be used in children aged above one, adults and the elderly. The amount of puffs appropriate depends on age:

Adults, adolescents and elderly:
 -4 to 8 puffs can be used every one and a half to three hours

Children aged 6 to 12:
 -Up to 4 puffs can be used every one and a half to three hours

Children under 6:
 -One puff for every 4 kg of body weight, up to a maximum of 4 puffs every one and a half to three hours.

Difflam Spray should only be applied to the mouth or throat and not any other areas of the body.


Difflam Spray is thought to be effective in reducing pain and inflammation in the throat and mouth.
If you feel that Difflam Spray is ineffective, you may be suffering from a more severe throat infection. If this is the case you may need to be prescribed a course of antibiotics. Difflam Spray can be used in combination with antibiotics.


An alternative to Difflam Spray is its generic form benzydamine spray. This contains the same active ingredient and is used in the same way. Generic versions of medicines tend to be cheaper than the branded variation.

Ultra Chloraseptic Anaesthetic throat spray is an alternative to Difflam Throat Spray. This spray provides targeted pain relief through anaesthetic agent benzocaine.

If you don’t feel comfortable using a spray, lozenges are a good alternative option - Tyrozets and Strepsils both contain numbing and antiseptic properties. These are designed to be sucked in the mouth slowly releasing an active ingredient which helps to soothe a sore throat.

Difflam Throat Spray Reviews

After using any treatment it is helpful to let others know about your experience. Reviews of an item help others know that medicines received are genuine, how well the treatment worked and any other issues to be aware of. We invite users to leave a review of both their treatment and the service that was provided. Click on the reviews tab to see if there has been any feedback on this item.


Can I use difflam spray and ibuprofen together?

Speak to your doctor or pharmacist before taking these medicines together. 

Can you get difflam spray over the counter?

Difflam is available as a pharmacy medicine and can be bought after completing a short questionnaire on medicine suitability on our website.

Can I purchase Difflam Spray anywhere else?

We are confident that at Simple Online Pharmacy we offer the lowest prices available, however if you would like to compare prices then search ‘difflam spray tesco’, ‘difflam spray asda’ and ‘difflam spray boots’ to check prices

Can I use Difflam Spray during pregnancy? 

If you are planning to conceive or are pregnant, consult your doctor or healthcare professional before for advice on taking this medicine.

Difflam Spray tonsillitis treatment?

Difflam spray offers short term relief from inflammation and pain in the throat. The spray works by reducing pain and inflammation in the throat after oral and dental surgery, mouth ulcers, colds and infections such as oral thrush. 

You should speak to your doctor for advice and guidance when experiencing tonsillitis symptoms.

Side Effects

Side Effects of Difflam Spray

As with any medication, it is possible you may experience side effects whilst using Difflam Spray.
Most commonly numbness, tingling or stinging sensation in the area to which the spray is applied.

Other less common side effects include:

  • Itching
  • Skin rash
  • Wheezing
  • Difficulty breathing
  • Anaphylactic and allergic reactions

You should not use Difflam Spray if you have a history of sensitivity to benzydamine.
You should speak to your pharmacist/doctor before using Difflam Spray if you are asthmatic or are sensitive to NSAIDs.  

For a full list of side effects, read the patient information leaflet that comes with this medication!

Info Leaflet

Before taking any medication, it is important to read the Patient Information Leaflet. You can find information leaflets for your medicines by typing them into the search bar at medicines.org, or by contacting us.


Directions of use for Difflam Spray

Direct the spray nozzle to the area of your mouth or throat that is sore. The appropriate number of puffs should be sprayed every one and a half to three hours as needed.


Pregnancy and Breastfeeding

If you are pregnant or breastfeeding you should consult your pharmacist or doctor before using this medication.


Order within for guaranteed next day delivery options

ClosePrice Checker
Save 14%Now £6.00 Was £6.99
The variation selected is currently out of stock.
Item added to bag. Click here to view bag.
Please select a size from above to proceed.
There are NHS prescriptions in your basket. Please complete the order first or remove NHS prescriptions from the basket.
Copyright © 2013 - 2024 Simple Online Pharmacy Ltd. All rights reserved.
Data security and protection policies available by request.
  • Digital Clinical
  • LegitScript approved
  • Registed Pharmacy
  • NHS pharmacy
  • Visa
  • mastercard