Syndol Headache Relief
  • Syndol Headache Relief

Syndol Headache Relief

From £4.95

Medication features

  • Contains Paracetamol, Codeine, Caffeine
  • Relief from acute headache and migraines
  • For 3 day use only 


Buy Syndol Headache Relief Online 

Syndol headache relief offers a tailored formulation which combines paracetamol, codeine and caffeine, to effectively relieve headache.

Syndol can also be used for the short term treatment of acute moderate pain which is not relieved by paracetamol, ibuprofen or aspirin alone.

Suitable for migraine, headache, rheumatic pain, period pain, toothache and neuralgia.

Not suitable for long term - 3 day use maximum. 

Taking too much opioid medicine, whether intentional or not, is called an overdose. This can be very serious and may cause death.

  • Confusion or hallucinations
  • Slurred speech
  • Lips or fingernails are blue or purple
  • Poor coordination or balance
  • Unresponsive or unconscious
  • Heavy or unusual snoring
  • Difficulty breathing or no breathing
  • Very small pupils in the eyes

Your family, friends, and carers should know these signs so they can take immediate action.  If you think that you or someone else has taken too much of their opioid medicine, dial 999 immediately. Please see this UK Government information for further advice.


What is in Syndol Headache tablets?

Syndol Tablets contain paracetamol, codeine, caffeine.

Why is there a maximum of 3 day use?

Syndo contains codeine which if used incorrectly can become addictive, so therefore it is advised that the medication is not taken for more than 3 consecutive days. If your pain has not subsided in this period, it is recommended that you speak to your own Doctor for advice.

Can I get addicted to Syndol headache tablets?

Syndol headache tablets will not become an addictive medication if the guidelines set out by the manufacturer are followed correctly. If only being taken for short term pain relief and for no more than 3 consecutive days there should be no issues.

The medication can become addictive if the guidelines are not followed correctly or if it is taken over long periods of time if you feel this is the case it is recommended that you speak to your Doctor.


Side Effects

Side effects of Solpadeine Max Soluble

As with any medication, there are risks of side effects when taking Syndol headache tablets. You should always read the patient information leaflet when taking a new medicine to make sure you're aware of the full list of side effects and cautions. If you have any unwanted side effects you should seek advice from your doctor, pharmacist or other healthcare professional.

Stop taking this medicine and seek medical advice from your doctor immediately if you experience any of the following:

Severe abdominal pain, dry mouth, nausea, and vomiting if you have recently had your gallbladder removed
Nervousness, dizziness, irritability, drowsiness or restlessness
Allergic reactions (this could be severe and present with symptoms like a skin rash, itching, facial swelling including the mouth or shortness of breath
Skin rash/peeling, mouth ulcers, itching or sweating
Breathing problems. (This is more common if you have had this side effect in the past when using other painkillers (for example, ibuprofen or aspirin)
Unexplained bruising/bleeding
Nausea, upset stomach, sudden weight loss, loss of appetite
Yellowing of the eyes and skin
Difficulty in urinating


Info Leaflet

Before taking any medication, it is important to read the Patient Information Leaflet. You can find information leaflets for your medicines by typing them into the search bar at, or by contacting us.


Warnings for Syndol headache tablets

This medicine contains codeine which can cause addiction if you take it continuously for more than 3 days. This can give you withdrawal symptoms from the medicine when you stop taking it.
If you take a painkiller for headaches for more than 3 days it can make them worse.
Do not take Syndol Tablets:

If you have ever had an allergic reaction to paracetamol, caffeine, codeine, other opioid painkillers or to any of the other ingredients
If you are taking other medicines containing paracetamol or codeine
If you are under 12 years:
For pain relief in children and adolescents (0-18 years of age) after removal of their tonsils or adenoids due to obstructive sleep apnoea syndrome
If you know that you metabolise very rapidly codeine into morphine
If you are breastfeeding.
Ask your doctor before you take this medicine:

If you have liver or kidney disease, including alcoholic liver disease
If you have bowel problems including blockage of your bowel
If you have had an operation to remove your gall bladder
Warnings and precautions
Codeine is transformed into morphine in the liver by an enzyme. Morphine is a substance that produces pain relief. Some people have a variation of this enzyme and this can affect people in different ways. In some people, morphine is not produced or produced in very small quantities, and it will not provide enough pain relief. Other people are more likely to get serious side effects because a very high amount of morphine is produced. If you notice any of the following side effects, you must stop taking this medicine and seek immediate medical advice: Slow or shallow breathing, confusion, sleepiness, small pupils, feeling or being sick, constipation, lack of appetite.

Driving and using machines
This medicine can affect your ability to drive as it may make you sleepy or dizzy.

Do not drive while taking this medicine until you know how it affects you. It is an offence to drive if this medicine affects your ability to drive. However, you would not be committing an offence if:

The medicine has been taken to treat a medical or dental problem and
You have taken it according to the information provided with the medicine and
It was not affecting your ability to drive safely

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