Wegovy Dose Schedule 

Wegovy is injected once a week, on the same day each week. When you first start taking Wegovy, the dose is increased every four weeks. This helps to reduce the risk of side effects by allowing your body to become accustomed to the drug. At Week 17, you will reach the full dose which you will continue for the rest of your treatment. The Wegovy dosing schedule is outlined below:

Wegovy Dosage Guide

You will have a separate pen for each Wegovy strength. Each pen contains four doses. You will need to adjust the pen to the correct dose yourself before injecting. Please see the patient information leaflet for more information.

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What is the Wegovy Dose for Weight Loss?

The standard dose of Wegovy for weight loss is 2.4mg once a week. However, you should not start taking this dose straight away; instead, you should gradually increase the dose over 17 weeks using the method outlined in the Wegovy dosage chart above.

Which Wegovy Doses are Available?

Wegovy is available in five different strengths. Typically, you should start off by taking 0.25mg of Wegovy each week for the first four weeks. The dose is gradually increased until you reach the full dose of 2.4mg a week. The different Wegovy doses are listed below:

Wegovy Dosage Chart

How Many Doses are in a Wegovy Pen?

Each Wegovy pen contains 4 doses of Wegovy. Between uses, you should store your Wegovy pens in the fridge. Once you have used all 4 doses in your Wegovy pen, you should dispose of it safely in a sharps bin. Do not attempt to reuse the needle.

How Often Do You Inject Wegovy?

Wegovy should be injected once a week. Inject Wegovy at any time on the same day each week. You do not need to take Wegovy with food. 

How Long Does Wegovy Stay in Your System?

Wegovy contains the active ingredient, semaglutide. After seven days, less than half of the active drug will remain in your body, however the rate at which your body clears the drug will slow down, so it can take over 40 days for you to be completely clear of the semaglutide in your system. 

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What Should You Do if You Miss a Dose of Wegovy?

If you miss a dose of Wegovy, what you should do depends on when your next dose is due. If your next dose is due within 48 hours, you should not take the missed dose. Simply take your next dose at the scheduled time. 

If your next dose is due in more than 2 days, take the missed dose as soon as possible. Then take the following dose at the usual scheduled time. If you have missed your Wegovy doses for more than two weeks, you should speak to your doctor for further advice on restarting Wegovy. 


Wegovy is injected once a week, on the same day each week.
When starting Wegovy, the dose is slowly increased over several months.
The starting dose of Wegovy is 0.25mg and the full dose of Wegovy is 2.4mg.

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Wegovy Patient Information Leaflet (medicines.org)