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Wegovy weight loss injections

Buy once-weekly Wegovy GLP-1 injection pens that help reduce appetite and supports sustainable weight loss.

4.7 39,000+ reviews
  • Once-weekly self-injection pen
  • Lose an average of 20.7% of your body weight in 72 weeks*
  • Shown to cut heart disease risk**
  • Once-weekly self-injection pen
  • Lose an average of 20.7% of your body weight in 72 weeks*
  • Shown to cut heart disease risk**

Select dose

Indicative starting dose for reference. Your clinician will determine the appropriate dose based on your medical assessment. Treatment may not be suitable for everyone.

*STEP UP, 72-week study of adults with obesity using Wegovy (semaglutide 2.4mg). Individual results vary. **SELECT study; Wegovy shown to cut the risk of major cardiovascular events by 20% in adults with obesity and existing heart disease. Individual results vary.

UK-registered pharmacy
Clinician-led prescribing
Speedy, discreet delivery

What is Wegovy?

Wegovy (semaglutide) is a once-weekly injection that helps reduce appetite and regulate blood sugar. It mimics the natural hormone GLP-1 to slow digestion, improve insulin release, and make you feel fuller for longer.

Wegovy Summary

A quick overview of key details.

Summary
PriceFrom £99 / Month
How it worksSuppresses appetite
EffectivenessUp to 20% body weight loss
EligibilityBMI over 30, or over 27 with a weight-related condition
Side effectsCommon side effects include nausea, diarrhoea, constipation
DosageStarting at 0.25mg once weekly. Maximum dosage of 2.4mg once weekly.

What is Wegovy?

Wegovy is a clinically proven, UK licensed weight loss treatment. Clinical trials have shown it can help achieve up to 20% body weight loss. It is a GLP-1 weight loss medication prescribed for people with a body mass index (BMI) over 30. It can also be prescribed for patients with a BMI of 27+ and a weight-related medical condition. The active ingredient semaglutide is manufactured by Novo Nordisk. It is the same active ingredient found in Ozempic, but Wegovy is specifically licensed for weight management.

Real Wegovy results from our patients

People come to us for different reasons, but most are looking for a safe, supported way to manage their weight.

20 %

of body weight lost (in studies) *

9 in 10

reported health improvements

7 in 10

reported increased confidence

* Based on clinical study results and patient-reported outcomes. Individual results vary.

Read our GLP-1 weight loss survey and key insights

39,000+ verified customer reviews

4.7 out of 5 stars from 39,000+ reviews 4.7 out of 5 Trustpilot
See all reviews

GB · 8 reviews

5 out of 5 stars Verified

Very reputable company

I like the way you had me wait until I uploaded a current picture when joining your company, and then wait until I was assessed by a doctor and had a decision. It proves you are a very reputable company and do not allow people to abuse the drug. It came packaged in an internally padded box with a cool pack, which I also appreciated. The service was spot on and my order went through nice and smooth.

GB · 38 reviews

5 out of 5 stars Verified

The experience has been life changing

The experience has been life changing for me. I have lost about 5 stone and still have another 2 stone to go, but I seem to be at a plateau. I am not hungry, so I am not overeating, and I am aware of eating to keep my body active, but there has been no weight change. I want to get to my ideal weight and then need advice on how to maintain that weight. I take vitamins to help with hair, skin and nails, and others have complimented me on how I look. It is not vanity, I just do not want to look worn out or haggard with weight loss.

GB · 33 reviews

5 out of 5 stars Verified

Fast, efficient, supportive and knowledgeable service

Simple Online Pharmacy has seen me through my weight loss journey. With their help and guidance, I have lost 5.5 stone and am now working towards a suitable maintenance level of Mounjaro. The service is quick, but there is always knowledgeable support in the background. I do not feel like a number, and my concerns are always answered in a professional way.

GB · 23 reviews

5 out of 5 stars Verified

Simple Online Pharmacy are a wonderful company

Simple Online Pharmacy are a wonderful company with great ethics. While on my weight loss journey, other pharmacies have tried to constantly push products onto me and push me to buy higher and higher doses. Simple Online Pharmacy do not send anything to entice me to buy products. Instead, they send links offering support and information to help me support myself. I love the podcasts available on their YouTube channel and the calibre of the people they interview. Their prices are reasonable and easy to find without having to submit a ton of information first, and their shipping is exemplary. They are always my first port of call and always will be.

GB · 5 reviews

5 out of 5 stars Verified

Quick and simple

Filled out a reasonably in-depth questionnaire, uploaded images and then prescription was dispatched for next day delivery within the hour. Very detailed how to use guide, couldn't be simpler.

GB · 1 review

5 out of 5 stars Verified

Great company to deal with...

This company is easy and reliable to deal with. They have your best interests in mind and are vigilant about checking in with you about your health which indicates that they actually care.

GB · 40 reviews

5 out of 5 stars Verified

Online Doctor - 5 stars

I have been using SOL pharmacy for sometime now and I can honestly say the support is available 24/7 for any questions that may arise. The use of the online doctor was easy to access and provided clear direction swiftly.

Wegovy prices

Treatment begins with a low starting dose, which may be gradually increased every four weeks based on your progress.

Dose Stage Price per pen
0.25mg Starter dose £99
0.5mg Titration £119
1mg Titration £125
1.7mg Titration £169
2.4mg Maintenance £189
7.2mg Extended maintenance £329

Prices are per pen. No subscription required. Your clinician will confirm the appropriate dose based on your assessment.

Start my assessment

Eligibility

Who Wegovy may be suitable for, and the core criteria a clinician will review.

Is it for me?

Wegovy should only be used to support weight loss if lifestyle changes like regular exercise and diet haven't been successful. Other GLP-1 medications are also available in the UK, including Saxenda, Mounjaro and Ozempic. Wegovy can be used for patients who have a BMI of over 30, or in patients with a BMI over 27, and other risk factors such as: Type 2 diabetes High cholesterol Obstructive sleep apnoea High blood pressure

Access & cost

Availability, access pathways, and pricing context.

Is Wegovy available on the NHS?

Wegovy (semaglutide) is available on the NHS through specialist weight management services for eligible patients. It may be prescribed if you have weight-related health problems and a BMI of 35 or higher (or 32.5 or higher for people of Asian, Chinese, Middle Eastern, Black African or African-Caribbean origin). In some cases, it may be offered to those with a BMI between 30 and 34.9 (or 27.5 and 32.4 for the above groups) if additional clinical criteria are met. Wegovy has limited availability on the NHS and is primarily prescribed privately for weight loss.

Can I buy Wegovy online in the UK?

Yes. For example, Simple Online Pharmacy offers Wegovy after a clinician reviews your eligibility through an online consultation.

How much does Wegovy cost?

Prices typically range from £99 to £329 per month, depending on the dose and prescription length.

What are alternatives to Wegovy?

Alternatives include Saxenda (liraglutide), Orlistat, or Mounjaro (tirzepatide). Consult with your clinician to determine the best option for you.

Results

What the weight loss results associated with Wegovy can look like. Individual results vary.

How effective is Wegovy?

Clinical trials show an average weight loss of 20% when using the 7.2mg dose combined with diet and exercise.

Can Wegovy help with other conditions?

While Wegovy (semaglutide) has shown great results for weight loss, research shows it might have additional benefits. The SELECT study, conducted worldwide with over 17,000 patients, aimed to demonstrate Wegovy's ability to reduce a patient's chances of experiencing a repeat cardiovascular event (such as a heart attack or stroke). The study appeared to be successful, showing a 20% risk reduction, meaning you are 20% less likely to have a heart attack or stroke if you have had one previously, independent of weight lost. This shows that Wegovy has specific beneficial properties on the heart. This is what sets Wegovy apart from other similar weight loss medications; it has significant evidence to back up its positive impact on reducing the risk of a secondary heart attack or stroke. So, if you have cardiovascular disease, such as a previous heart attack or stroke, and are in two minds as to which weight loss option is for you, this may be a point of difference. If you have any questions about our treatment options and their benefits, please contact our clinical team.

How much weight can I lose with Wegovy?

Clinical trials show an average weight loss of 20% when using the 7.2mg dose combined with diet and exercise.

How long until I see results?

Most users notice appetite suppression within days, while significant weight loss typically begins after 8–12 weeks.

Will I regain weight if I stop Wegovy?

Weight regain is possible without ongoing lifestyle changes such as healthier eating and increased physical activity. Wegovy is intended for long-term use under medical supervision.

Does Wegovy improve obesity-related conditions?

Yes, it can reduce risks of heart disease, type 2 diabetes, and improve overall metabolic health.

Mounjaro vs Wegovy at a glance

Both Wegovy and Mounjaro are once-weekly injections prescribed for weight loss. They're effective in different ways, and the right choice depends on how your body responds, not just the headline numbers.

Quick comparison

Mounjaro
Wegovy
How it works
GLP-1 + GIP hormones
GLP-1 hormone
Weight loss (studies)*
~20–22%
~15–20%
Dosing
Weekly injection
Weekly injection
Tolerability
Some people find dose increases easier
Well-established, varies by person
Typical cost
Often higher at equivalent doses
Often lower at equivalent doses

*Based on separate clinical trials. No direct head-to-head studies. Results vary.

How it works

How Wegovy works in the body to support appetite regulation and weight management.

How it works

Wegovy works by mimicking the action of GLP-1, a natural hormone produced in the gut after eating. This hormone plays a key role in appetite regulation. Its main effects are: It helps regulate appetite, making it easier to eat less It slows stomach emptying, making you feel fuller for longer Both actions lead to eating fewer calories, which results in weight loss.

How to take and dosage

How Wegovy is taken, how dosing progresses, and what to expect during titration.

Dosage

The dosage table below outlines the recommended titration for Wegovy when used for weight loss.

WeeksDoseNotes
1-40.25 mg once weeklyInitial dose for titration
5-80.5 mg once weeklyAssess tolerance before increase
9-121 mg once weeklyAssess tolerance before increase
13-161.7 mg once weeklyMonitor for efficacy and tolerability
17 onwards2.4 mg once weeklyMaintenance dose if well tolerated

How is Wegovy administered?

It is administered as a once-weekly subcutaneous injection in the abdomen, thigh, or upper arm.

What is the dosage schedule?

Begin at 0.25mg per week for 4 weeks, then gradually increase every 4 weeks to a maintenance dose of 2.4mg per week. Patients may also choose to increase their dose further, to 7.2mg per week (given as three 2.4mg doses).

What if I miss a dose?

Take the missed dose within 5 days. If more than 5 days pass, skip the missed dose and resume your regular schedule.

Can I adjust the dose myself?

No. You must follow the prescribed titration schedule to minimise side effects.

How many doses of Wegovy are in one pen?

Each Wegovy pre-filled pen contains four once-weekly doses and lasts four weeks. Pens are colour-coded to match your current stage in the titration schedule.

How to get Wegovy

Our clinician-led process for accessing Wegovy safely and discreetly.

Online health assessment screnshot on a mobile device

Complete a simple assessment

Answer questions about your health, lifestyle, and goals.

Clinician responding to a patient assessment

Your assessment is reviewed by a clinician

A UK-registered prescriber carefully reviews your assessment to ensure treatment is safe and suitable for you.

Discreet pharmacy delivery box being prepared

Receive discreet delivery

Your medication is dispensed by our registered pharmacy and delivered directly to your door in plain packaging.

View of the support portal dashboard

Stay supported

Schedule reviews with our specialist teams to monitor your progress and provide support throughout your journey.

What our expert says

Wegovy has been a game-changer for many patients struggling with weight management. By helping to control hunger and cravings, it allows people to make sustainable changes to their eating habits and focus on their overall health journey.

Abdal Alvi, Chief Clinical Officer at Simple Online Pharmacy

Abdal Alvi

Chief Clinical Officer

Our expert team

Our committed clinical team, consisting of expert doctors, pharmacists, dietitians, and health coaches, is dedicated to supporting you at every stage of your health journey. Join over 1,000,000 UK patients who trust Simple Online Pharmacy with their health.

Understanding side effects

The most common early side effects. For most people it improves within the first few weeks as the body adjusts.

Nausea

"Will I feel sick all the time?"

Reality: The most common early side effect, particularly when starting or increasing your dose. For most people it settles within a few days to a couple of weeks as the body adjusts.

Diarrhoea & constipation

"What if my body reacts badly?"

Reality: Both are very common early on. Weight loss injections slow digestion, which can disrupt normal bowel patterns. They're usually manageable and improve as your body settles.

Bloating & burping

"Will I feel uncomfortable all the time?"

Reality: Bloating, gas and burping can occur as your digestive system adjusts to the medication. They're more common early in treatment and tend to ease over time.

Fatigue

"Why do I feel so drained?"

Reality: Fatigue is a common side effect of weight loss injections. It's not fully understood, but is likely linked to lower calorie intake, blood sugar changes, or disrupted sleep. It usually improves as your body adapts.

Side effects & safety

Common side effects and key safety considerations.

Side effects of Wegovy

The most common side effects with Wegovy affect the digestive system. These can include things like nausea, vomiting, diarrhoea and constipation. Most patients should see these effects subside after a few days. Other common side effects include: Feeling weak or tired Dizziness Headache Injection site reactions

What are common side effects?

Common side effects include nausea, vomiting, diarrhoea, constipation, and abdominal pain. These often resolve as the body adjusts to treatment.

How can I reduce nausea on Wegovy?

Eating smaller meals, avoiding very fatty or rich foods, and staying well hydrated can help. Nausea is most common when starting or increasing your dose and usually eases over time. If it is severe or persistent, speak to your clinician.

Can Wegovy cause thyroid cancer?

Animal studies have linked semaglutide to thyroid tumours. Wegovy should be avoided if you or any family members have a history of medullary thyroid carcinoma or MEN syndrome.

Is Wegovy safe during pregnancy?

No. Wegovy should not be used during pregnancy, as it may harm the foetus. Treatment should be stopped at least 2 months before a planned pregnancy. Use effective contraception while on treatment.

Can I use Wegovy while breastfeeding?

No. Wegovy is not recommended while breastfeeding. Speak to your clinician before starting or continuing treatment if you are breastfeeding or planning to.

Does Wegovy affect the contraceptive pill?

Wegovy has not been shown to reduce the effectiveness of the oral hormonal contraceptive pill. Unlike some other weight loss medicines that require additional barrier contraception during dose changes, this is not necessary with Wegovy.

Interactions

Medication and lifestyle interactions to be aware of.

Does Wegovy interact with other medications?

Wegovy may increase the risk of hypoglycaemia if used with insulin or sulfonylureas. Always inform your clinician of all medicines you are taking before starting treatment.

Can I drink alcohol with Wegovy?

Moderate alcohol consumption is generally acceptable when using Wegovy. However, excessive drinking may worsen gastrointestinal side effects. It is also worth noting that many alcoholic drinks are calorie-dense, which can hinder your ability to lose weight.

Wegovy Titration Guide

Your clinician will guide your dose increases. This schedule shows the typical 4-week steps for Wegovy.

This table shows the Wegovy titration schedule across 20 weeks, organized by dosage levels from 0.25mg to 2.4mg. Each dosage level spans 4 weeks, with instructions for ordering and completing each pen.

0.25mg
Week 1
Week 2
Week 3 Order next pen
Week 4 Pen finished
0.5mg
Week 5
Week 6
Week 7 Order next pen
Week 8 Pen finished
1mg
Week 9
Week 10
Week 11 Order next pen
Week 12 Pen finished
1.7mg
Week 13
Week 14
Week 15 Order next pen
Week 16 Pen finished
2.4mg
Week 17
Week 18
Week 19 Order next pen
Week 20 Pen finished

FAQs

Common questions about Wegovy, including comparisons, storage, access, and practical next steps.

Is Wegovy safe?

Yes, when prescribed appropriately. It is MHRA-approved but is contraindicated for individuals with a history of medullary thyroid carcinoma, pancreatitis, or those who are pregnant.

How many Wegovy pens are in a box?

Each box of Wegovy contains one pre-filled pen, which provides four once-weekly doses. One pen lasts four weeks of treatment.

Is Wegovy the same as Ozempic?

Both contain semaglutide, but Wegovy is approved for weight loss at higher doses (up to 2.4mg weekly), while Ozempic is licensed for type 2 diabetes at lower doses.

Storage

Storage guidance for Wegovy at home and while travelling.

How should I store Wegovy?

Unopened pens should be refrigerated at 2–8°C. Once opened, store Wegovy at room temperature (≤30°C) and use within 42 days.

Can I travel with Wegovy?

Yes. Keep unopened pens in a fridge (36–46°F / 2–8°C) and use a cool bag or insulated case with gel packs while travelling with Wegovy. Avoid heat or freezing. Once opened, a pen can be kept at room temperature (below 86°F / 30°C) for up to 30 days. Always carry pens in your hand luggage, not checked baggage.

Aamina Rafiq, Superintendent Pharmacist at Simple Online Pharmacy

Reviewed by

Aamina Rafiq

Superintendent Pharmacist GPhC: 2216332

This page has been reviewed by our clinical team to ensure it is clear, accurate, and up to date.

Last updated: 3 May 2026